Clinical factors influencing corrected count increment

Shamee Shastry, Rajendra Chaudhary

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Refractoriness to platelet transfusions is a common clinical problem. The present study was conducted to look into patient characteristics affecting the corrected count increment in a tertiary care referral hospital. A total of 161 aphaeresis platelet units were transfused to 40 patients with varied clinical diagnoses. The mean platelet increment was 17,789/mm3. Median corrected count increment was 7344 and percentage platelet recovery was 22.82%. Logistic regression analysis revealed significant influence of splenomegaly and anti-platelet drugs on refractoriness. Fever, bleeding, sepsis, disseminated intravascular coagulation and cyclosporine use, though more common in the patients with refractoriness they were not statistically significant.

Original languageEnglish
Pages (from-to)327-330
Number of pages4
JournalTransfusion and Apheresis Science
Volume47
Issue number3
DOIs
Publication statusPublished - 01-12-2012

All Science Journal Classification (ASJC) codes

  • Hematology

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