Clinical spectrum of rheumatic fever and rheumatic heart disease: A 10 year experience in an Urban Area of South India

Nitin Joseph, Deepak Madi, Ganesh S. Kumar, Maria Nelliyanil, Vittal Saralaya, Rai Sharada

Research output: Contribution to journalArticle

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Abstract

Background: Rheumatic fever (RF) is an important problem concerning developing countries like India. Rheumatic heart disease (RHD) is one of the most readily preventable chronic diseases. Aim: This study was done to find out the clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as to suggest better case management strategies. Materials and Methods: Clinical records of 51 RF and 71 RHD cases admitted in tertiary care hospitals in Mangalore between 2001 and 2010 were reviewed retrospectively. Results: Mean age of RF cases were 17.4 ± 12.1 years and RHD cases were 33.2 ± 18.6 years. More than half of RF and RHD cases were males. Commonest risk factors among RF cases were poor socioeconomic status (60.4%), history of upper respiratory tract infection before disease onset (58.8%) and undernutrition (35.3%). Commonest clinical manifestation among RF cases was fever 39 (76.5%) followed by polyarthritis 34 (66.7%). Commonest valvular lesions among RHD cases was mitral stenosis with mitral regurgitation found in 42.9% cases. Compliance of patients with prophylactic antibiotics was found to be 37 (30.3%). Mortality rate was significantly more among RHD cases (P = 0.0399). Conclusions: Improvement of socioeconomic and nutritional factors is an important task required for primary prophylaxis and of compliance for secondary prophylaxis of RF.

Original languageEnglish
Pages (from-to)647-652
Number of pages6
JournalNorth American Journal of Medical Sciences
Volume5
Issue number11
DOIs
Publication statusPublished - 01-11-2013

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Rheumatic Heart Disease
Rheumatic Fever
antineoplaston A10
India
Mitral Valve Stenosis
Case Management
Mitral Valve Insufficiency
Tertiary Healthcare
Patient Compliance
Tertiary Care Centers
Social Class
Malnutrition
Respiratory Tract Infections
Developing Countries
Compliance
Arthritis
Chronic Disease
Fever
Anti-Bacterial Agents
Mortality

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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title = "Clinical spectrum of rheumatic fever and rheumatic heart disease: A 10 year experience in an Urban Area of South India",
abstract = "Background: Rheumatic fever (RF) is an important problem concerning developing countries like India. Rheumatic heart disease (RHD) is one of the most readily preventable chronic diseases. Aim: This study was done to find out the clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as to suggest better case management strategies. Materials and Methods: Clinical records of 51 RF and 71 RHD cases admitted in tertiary care hospitals in Mangalore between 2001 and 2010 were reviewed retrospectively. Results: Mean age of RF cases were 17.4 ± 12.1 years and RHD cases were 33.2 ± 18.6 years. More than half of RF and RHD cases were males. Commonest risk factors among RF cases were poor socioeconomic status (60.4{\%}), history of upper respiratory tract infection before disease onset (58.8{\%}) and undernutrition (35.3{\%}). Commonest clinical manifestation among RF cases was fever 39 (76.5{\%}) followed by polyarthritis 34 (66.7{\%}). Commonest valvular lesions among RHD cases was mitral stenosis with mitral regurgitation found in 42.9{\%} cases. Compliance of patients with prophylactic antibiotics was found to be 37 (30.3{\%}). Mortality rate was significantly more among RHD cases (P = 0.0399). Conclusions: Improvement of socioeconomic and nutritional factors is an important task required for primary prophylaxis and of compliance for secondary prophylaxis of RF.",
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Clinical spectrum of rheumatic fever and rheumatic heart disease : A 10 year experience in an Urban Area of South India. / Joseph, Nitin; Madi, Deepak; Kumar, Ganesh S.; Nelliyanil, Maria; Saralaya, Vittal; Sharada, Rai.

In: North American Journal of Medical Sciences, Vol. 5, No. 11, 01.11.2013, p. 647-652.

Research output: Contribution to journalArticle

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AU - Madi, Deepak

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AU - Nelliyanil, Maria

AU - Saralaya, Vittal

AU - Sharada, Rai

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N2 - Background: Rheumatic fever (RF) is an important problem concerning developing countries like India. Rheumatic heart disease (RHD) is one of the most readily preventable chronic diseases. Aim: This study was done to find out the clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as to suggest better case management strategies. Materials and Methods: Clinical records of 51 RF and 71 RHD cases admitted in tertiary care hospitals in Mangalore between 2001 and 2010 were reviewed retrospectively. Results: Mean age of RF cases were 17.4 ± 12.1 years and RHD cases were 33.2 ± 18.6 years. More than half of RF and RHD cases were males. Commonest risk factors among RF cases were poor socioeconomic status (60.4%), history of upper respiratory tract infection before disease onset (58.8%) and undernutrition (35.3%). Commonest clinical manifestation among RF cases was fever 39 (76.5%) followed by polyarthritis 34 (66.7%). Commonest valvular lesions among RHD cases was mitral stenosis with mitral regurgitation found in 42.9% cases. Compliance of patients with prophylactic antibiotics was found to be 37 (30.3%). Mortality rate was significantly more among RHD cases (P = 0.0399). Conclusions: Improvement of socioeconomic and nutritional factors is an important task required for primary prophylaxis and of compliance for secondary prophylaxis of RF.

AB - Background: Rheumatic fever (RF) is an important problem concerning developing countries like India. Rheumatic heart disease (RHD) is one of the most readily preventable chronic diseases. Aim: This study was done to find out the clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as to suggest better case management strategies. Materials and Methods: Clinical records of 51 RF and 71 RHD cases admitted in tertiary care hospitals in Mangalore between 2001 and 2010 were reviewed retrospectively. Results: Mean age of RF cases were 17.4 ± 12.1 years and RHD cases were 33.2 ± 18.6 years. More than half of RF and RHD cases were males. Commonest risk factors among RF cases were poor socioeconomic status (60.4%), history of upper respiratory tract infection before disease onset (58.8%) and undernutrition (35.3%). Commonest clinical manifestation among RF cases was fever 39 (76.5%) followed by polyarthritis 34 (66.7%). Commonest valvular lesions among RHD cases was mitral stenosis with mitral regurgitation found in 42.9% cases. Compliance of patients with prophylactic antibiotics was found to be 37 (30.3%). Mortality rate was significantly more among RHD cases (P = 0.0399). Conclusions: Improvement of socioeconomic and nutritional factors is an important task required for primary prophylaxis and of compliance for secondary prophylaxis of RF.

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