Clinical study of cutaneous drug reactions in 80 patients

S. Sehgal, C. Balachandran, S. Shenoi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Eighty patients (46 males, 34 females) with cutaneous drug eruption were studied. Maculopapular rash was the commonest reaction seen in 46 cases, others being purpuro in 7, acneiform in 6, SJS/ TEN in 5, FIDE in 5, EM in 3, exfoliative dermatitis in 2, AEGP in 2, pustular and eczematous reaction in one each. Majority of the patients were in 21-30 year age group, the youngest being 3 years and the oldest 76 years. The incriminated drugs were NSAIDS in 28, antipsychotics in 26, antibiotics in 24, antileprotics / antitubercular in 8, steroids in 5, antimitotics in 4 and cardiac drugs in 3 cases. Histopathologicol features were compatible with the clinical lesions in most of the cases. The commonest immunoreactant in direct immunofluorescence was C3 and fibrin.

Original languageEnglish
Pages (from-to)6-7
Number of pages2
JournalIndian Journal of Dermatology, Venereology and Leprology
Volume69
Issue number1
Publication statusPublished - 01-01-2003

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Exfoliative Dermatitis
Drug Eruptions
Antimitotic Agents
Direct Fluorescent Antibody Technique
Skin
Exanthema
Fibrin
Pharmaceutical Preparations
Antipsychotic Agents
Age Groups
Steroids
Anti-Bacterial Agents
Clinical Studies

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Infectious Diseases

Cite this

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Clinical study of cutaneous drug reactions in 80 patients. / Sehgal, S.; Balachandran, C.; Shenoi, S.

In: Indian Journal of Dermatology, Venereology and Leprology, Vol. 69, No. 1, 01.01.2003, p. 6-7.

Research output: Contribution to journalArticle

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