Clinicomicrobiological insight into bacteremia due to gram positive cocci

Soumya Shrigiri, Sevitha Bhat, K. Archana Bhat

Research output: Contribution to journalArticle

Abstract

Introduction: Bacteremia due to Gram positive cocci poses a challenge to clinicians due to the delay in diagnosis and multidrug resistance among these bugs. Aim: To study the associated infections, risk factors& antibiotic resistance in Gram positive cocci, to note antibiotic treatment and outcome in bacteremia. Materials and Method: Observational study was carried out in Microbiology laboratory of a tertiary care centre. Blood samples were cultured using BacT/ALERT system. Antibiotic susceptibility pattern was done by Vitek 2 compact system. Results: Enterococcus faecalis and Staphylococcus aureus were the most common isolates of clinically significant Gram positive bacteremia. Skin and soft tissue infections, infective endocarditis, urosepsis and biliary tract infections were the common sources. Health care related infections (55%) were predominant in contrast to hospital acquired bacteremia (15%) indicating that prior invasive procedures increases the risk of blood stream infection. Mortality of 34% was observed. Conclusion:Timely diagnosis of sepsis, identification of risk factors and co morbidities, choosing the appropriate antibiotic therapy is crucial in the management of Gram positive bacteremia.

Original languageEnglish
Pages (from-to)350-356
Number of pages7
JournalIndian Journal of Public Health Research and Development
Volume10
Issue number9
DOIs
Publication statusPublished - 09-2019

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Gram-Positive Cocci
Bacteremia
Anti-Bacterial Agents
Infection
Soft Tissue Infections
Enterococcus faecalis
Biliary Tract
Multiple Drug Resistance
Microbial Drug Resistance
Endocarditis
Microbiology
Tertiary Care Centers
Observational Studies
Staphylococcus aureus
Sepsis
Morbidity
Delivery of Health Care
Skin
Mortality

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

Cite this

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abstract = "Introduction: Bacteremia due to Gram positive cocci poses a challenge to clinicians due to the delay in diagnosis and multidrug resistance among these bugs. Aim: To study the associated infections, risk factors& antibiotic resistance in Gram positive cocci, to note antibiotic treatment and outcome in bacteremia. Materials and Method: Observational study was carried out in Microbiology laboratory of a tertiary care centre. Blood samples were cultured using BacT/ALERT system. Antibiotic susceptibility pattern was done by Vitek 2 compact system. Results: Enterococcus faecalis and Staphylococcus aureus were the most common isolates of clinically significant Gram positive bacteremia. Skin and soft tissue infections, infective endocarditis, urosepsis and biliary tract infections were the common sources. Health care related infections (55{\%}) were predominant in contrast to hospital acquired bacteremia (15{\%}) indicating that prior invasive procedures increases the risk of blood stream infection. Mortality of 34{\%} was observed. Conclusion:Timely diagnosis of sepsis, identification of risk factors and co morbidities, choosing the appropriate antibiotic therapy is crucial in the management of Gram positive bacteremia.",
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Clinicomicrobiological insight into bacteremia due to gram positive cocci. / Shrigiri, Soumya; Bhat, Sevitha; Archana Bhat, K.

In: Indian Journal of Public Health Research and Development, Vol. 10, No. 9, 09.2019, p. 350-356.

Research output: Contribution to journalArticle

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