Clitoria ternatea (Linn) root extract treatment during growth spurt period enhances learning and memory in rats

K. S. Rai, K. D. Murthy, K. S. Karanth, M. S. Rao

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Neonatal rat pups (7 days old) were intubated with either 50 mg/kg body weight or 100 mg/kg body weight of aqueous root extract of Clitoria ternatea (CTR) for 30 days. These rats were then subjected to open field, two compartment passive avoidance and spatial learning (T-Maze) tests (i) immediately after the treatment and (ii) 30 days after the treatment, along with age matched normal and saline control rats. Results showed no change in open field behaviour, but showed improved retention and spatial learning performance at both time points of behavioural tests, indicating the memory enhancing property of CTR which implicates a permanent change in the brain of CTR treated rats.

Original languageEnglish
Pages (from-to)305-313
Number of pages9
JournalIndian Journal of Physiology and Pharmacology
Volume45
Issue number3
Publication statusPublished - 03-09-2001

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Clitoria
Learning
Growth
Body Weight
Avoidance Learning
Brain

All Science Journal Classification (ASJC) codes

  • Physiology
  • Pharmacology
  • Physiology (medical)

Cite this

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Clitoria ternatea (Linn) root extract treatment during growth spurt period enhances learning and memory in rats. / Rai, K. S.; Murthy, K. D.; Karanth, K. S.; Rao, M. S.

In: Indian Journal of Physiology and Pharmacology, Vol. 45, No. 3, 03.09.2001, p. 305-313.

Research output: Contribution to journalArticle

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