Clitoria ternatea root extract enhances acetylcholine content in rat hippocampus

K.S. Rai, K.D. Murthy, K.S. Karanth, K. Nalini, M Rao, K.K. Srinivasan

Research output: Contribution to journalArticle

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Abstract

Treatment with 100 mg/kg of Clitoria ternatea aqueous root extract (CTR), for 30 days in neonatal and young adult age groups of rat, significantly increased acetylcholine (ACh) content in their hippocampi as compared to age matched controls. Increase in ACh content in their hippocampus may be the neurochemical basis for their improved learning and memory. © 2002 Elsevier Science B.V. All rights reserved.
Original languageEnglish
Pages (from-to)685-689
Number of pages5
JournalFitoterapia
Volume73
Issue number7-8
DOIs
Publication statusPublished - 2002

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Clitoria
Acetylcholine
Hippocampus
Young Adult
Age Groups
Learning
Therapeutics

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Rai, K. S., Murthy, K. D., Karanth, K. S., Nalini, K., Rao, M., & Srinivasan, K. K. (2002). Clitoria ternatea root extract enhances acetylcholine content in rat hippocampus. Fitoterapia, 73(7-8), 685-689. https://doi.org/10.1016/S0367-326X(02)00249-6
Rai, K.S. ; Murthy, K.D. ; Karanth, K.S. ; Nalini, K. ; Rao, M ; Srinivasan, K.K. / Clitoria ternatea root extract enhances acetylcholine content in rat hippocampus. In: Fitoterapia. 2002 ; Vol. 73, No. 7-8. pp. 685-689.
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abstract = "Treatment with 100 mg/kg of Clitoria ternatea aqueous root extract (CTR), for 30 days in neonatal and young adult age groups of rat, significantly increased acetylcholine (ACh) content in their hippocampi as compared to age matched controls. Increase in ACh content in their hippocampus may be the neurochemical basis for their improved learning and memory. {\circledC} 2002 Elsevier Science B.V. All rights reserved.",
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note = "Cited By :45 Export Date: 10 November 2017 CODEN: FTRPA Correspondence Address: Rai, K.S.; Department of Physiology, Kasturba Medical College, Manipal Pin 576119, KRN, India; email: kiranmai_rai2001@yahoo.com Chemicals/CAS: Acetylcholine, 51-84-3; Plant Extracts References: Rai, K.S., Murthy, K.D., Karanth, K.S., Rao, M.S., (2001) Indian J Physiol Pharmacol, 45 (3), p. 305; Sharma, P., (1988) Dravyaguna vignana, 2, p. 3. , Varanasi: Chaukambha Vishwabharathi Academy; Warrier, P.K., (1994) Indian medicinal plants, 2, p. 129. , Madras: Orient Longman Ltd; Sivaranjan, V.V., Indira, B., (1994) Ayurvedic drugs and their plant sources, p. 425. , New Delhi: Oxford & IBH Publishers Pvt., Ltd; Dash, P.K., Mistry, I.V., Rao, A.R., Patel, K.S., (1996) Ayurveda, p. 12; Sathyavathi, G.V., Gupta, A.K., Tandon, N., Medicinal plants of India (1976) Indian council of medical research, 1, p. 18. , G.V. Sathyavathi, A.K. Gupta, & N. Tandon. New Delhi: Cambridge Printing Works; Sharma, R.K., Bhagwan, D., (1996) Caraka samhitha, 3, p. 46. , New Delhi: Chaukambha Orientalia; Rai, K.S., Murthy, K.D., Karanth, K.S., Rao, M.S., (2000) 3rd FIPS Congress, p. 45. , (Abstract) In Souvenier; Kulkarni, C., Pattanshetty, J.R., Amruthraj, G., (1988) Indian J Exp Biol, 26 (12), p. 957; Taranalli, A.D., Cheeramkuzhy, T.C., (2000) Pharm Biol, 38 (1), p. 51; Harborne, J.B., (1973) Phytochemical method, pp. 1-50. , London, Chapman and Hall Ltd; Trease, C.E., Evans, V.C., (1984) Textbook of Pharmocognosy, 13th Ed., pp. 542-563. , London: Balliere Tindall; Eelman, J.H., (1969) J Neurochem, 16, p. 135; Bartus, R.T., Dean, L.R., Beer, B., Lippa, A.S., (1982) Science, 217, p. 408; Nishizaki, T., Matsuoka, T., Nomura, T., Kondoh, T., Watabe, S., Shiotani, T., Yoshii, M., (2000) Alzheimer. Dis Assoc Disord, (SUPPL. 1), pp. S82-S94; Rhodes, M.E., Li, P.K., Flood, J.F., Johnson, D.A., (1996) Brain Res, 733, p. 284; Moore, H., Stuckman, S., Sarter, M., Bruno, J.P., (1995) Synapse, 21, p. 324",
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Rai, KS, Murthy, KD, Karanth, KS, Nalini, K, Rao, M & Srinivasan, KK 2002, 'Clitoria ternatea root extract enhances acetylcholine content in rat hippocampus', Fitoterapia, vol. 73, no. 7-8, pp. 685-689. https://doi.org/10.1016/S0367-326X(02)00249-6

Clitoria ternatea root extract enhances acetylcholine content in rat hippocampus. / Rai, K.S.; Murthy, K.D.; Karanth, K.S.; Nalini, K.; Rao, M; Srinivasan, K.K.

In: Fitoterapia, Vol. 73, No. 7-8, 2002, p. 685-689.

Research output: Contribution to journalArticle

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T1 - Clitoria ternatea root extract enhances acetylcholine content in rat hippocampus

AU - Rai, K.S.

AU - Murthy, K.D.

AU - Karanth, K.S.

AU - Nalini, K.

AU - Rao, M

AU - Srinivasan, K.K.

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Y1 - 2002

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AB - Treatment with 100 mg/kg of Clitoria ternatea aqueous root extract (CTR), for 30 days in neonatal and young adult age groups of rat, significantly increased acetylcholine (ACh) content in their hippocampi as compared to age matched controls. Increase in ACh content in their hippocampus may be the neurochemical basis for their improved learning and memory. © 2002 Elsevier Science B.V. All rights reserved.

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DO - 10.1016/S0367-326X(02)00249-6

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