CNS toxoplasmosis presenting with obstructive hydrocephalus in patients of retroviral disease-A case series

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

CNS toxoplasmosis presenting as hydrocephalus is a very rare entity. We present three cases of HIV positive patients whose brain imaging revealed hydrocephalus and who improved with anti toxoplasma medication along with intravenous steroids and did not require any CSF shunting procedures. The mechanism of hydrocephalus in CNS toxoplasmosis is usually due to compression of CSF outflow pathway by ring enhancing lesions but even in their absence hydrocephalus can be rarely seen due to ventriculitis. Hence in HIV positive patients with unexplained hydrocephalus CNS toxoplasmosis should be considered and such patients if started on treatment early have a good prognosis without requiring neurosurgical intervention.

Original languageEnglish
Pages (from-to)214-216
Number of pages3
JournalMedical Journal of Malaysia
Volume67
Issue number2
Publication statusPublished - 01-12-2012

Fingerprint

Toxoplasmosis
Hydrocephalus
HIV
Toxoplasma
Neuroimaging
Steroids

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

@article{2214f444a5b14c048a456f3d9dc79f3d,
title = "CNS toxoplasmosis presenting with obstructive hydrocephalus in patients of retroviral disease-A case series",
abstract = "CNS toxoplasmosis presenting as hydrocephalus is a very rare entity. We present three cases of HIV positive patients whose brain imaging revealed hydrocephalus and who improved with anti toxoplasma medication along with intravenous steroids and did not require any CSF shunting procedures. The mechanism of hydrocephalus in CNS toxoplasmosis is usually due to compression of CSF outflow pathway by ring enhancing lesions but even in their absence hydrocephalus can be rarely seen due to ventriculitis. Hence in HIV positive patients with unexplained hydrocephalus CNS toxoplasmosis should be considered and such patients if started on treatment early have a good prognosis without requiring neurosurgical intervention.",
author = "A. Basavaprabhu and M. Soundarya and M. Deepak and Satish Rao",
year = "2012",
month = "12",
day = "1",
language = "English",
volume = "67",
pages = "214--216",
journal = "Medical Journal of Malaysia",
issn = "0300-5283",
publisher = "Malaysian Medical Association",
number = "2",

}

TY - JOUR

T1 - CNS toxoplasmosis presenting with obstructive hydrocephalus in patients of retroviral disease-A case series

AU - Basavaprabhu, A.

AU - Soundarya, M.

AU - Deepak, M.

AU - Rao, Satish

PY - 2012/12/1

Y1 - 2012/12/1

N2 - CNS toxoplasmosis presenting as hydrocephalus is a very rare entity. We present three cases of HIV positive patients whose brain imaging revealed hydrocephalus and who improved with anti toxoplasma medication along with intravenous steroids and did not require any CSF shunting procedures. The mechanism of hydrocephalus in CNS toxoplasmosis is usually due to compression of CSF outflow pathway by ring enhancing lesions but even in their absence hydrocephalus can be rarely seen due to ventriculitis. Hence in HIV positive patients with unexplained hydrocephalus CNS toxoplasmosis should be considered and such patients if started on treatment early have a good prognosis without requiring neurosurgical intervention.

AB - CNS toxoplasmosis presenting as hydrocephalus is a very rare entity. We present three cases of HIV positive patients whose brain imaging revealed hydrocephalus and who improved with anti toxoplasma medication along with intravenous steroids and did not require any CSF shunting procedures. The mechanism of hydrocephalus in CNS toxoplasmosis is usually due to compression of CSF outflow pathway by ring enhancing lesions but even in their absence hydrocephalus can be rarely seen due to ventriculitis. Hence in HIV positive patients with unexplained hydrocephalus CNS toxoplasmosis should be considered and such patients if started on treatment early have a good prognosis without requiring neurosurgical intervention.

UR - http://www.scopus.com/inward/record.url?scp=84866468557&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866468557&partnerID=8YFLogxK

M3 - Article

C2 - 22822648

AN - SCOPUS:84866468557

VL - 67

SP - 214

EP - 216

JO - Medical Journal of Malaysia

JF - Medical Journal of Malaysia

SN - 0300-5283

IS - 2

ER -