Coexistent gastric primary choriocarcinoma and adenocarcinoma

Muktha R. Pai, Alka M. Mathai, Suneet Kumar, Shivananda Prabhu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Choriocarcinomas are commonly gestational and intrauterine or gonadal in origin. Nongestational and extragonadal disease, especially in the stomach is extremely rare with a poorer prognosis and early metastasis. We herein describe a case of primary gastric choriocarcinoma with liver metastasis in a 69-year-old male. The patient presented with abdominal pain and irregular bowel habits of one month duration. Both endoscopic and radiographic imaging revealed an ulcerated and necrotic circumferential tumor in the pyloric antrum of the stomach. The histopathologic findings of the resected tumor were that of an extensively necrotic and hemorrhagic neoplasm with combined choriocarcinomatous and adenocarcinomatous element. A strongly positive immunohistochemical staining for - subunit of human chorionic gonadotropin (-HCG) in the choriocarcinomatous component and a proper correlation with elevated serum -HCG levels confirmed the diagnosis.

Original languageEnglish
Pages (from-to)537-539
Number of pages3
JournalIndian Journal of Pathology and Microbiology
Volume52
Issue number4
DOIs
Publication statusPublished - 01-10-2009
Externally publishedYes

Fingerprint

Choriocarcinoma
Stomach
Adenocarcinoma
Neoplasm Metastasis
Pyloric Antrum
Neoplasms
Chorionic Gonadotropin
Abdominal Pain
Habits
Staining and Labeling
Liver
Serum

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Microbiology (medical)

Cite this

Pai, Muktha R. ; Mathai, Alka M. ; Kumar, Suneet ; Prabhu, Shivananda. / Coexistent gastric primary choriocarcinoma and adenocarcinoma. In: Indian Journal of Pathology and Microbiology. 2009 ; Vol. 52, No. 4. pp. 537-539.
@article{ecd5b1c4e394422fbd2bf2c5fe7a64c6,
title = "Coexistent gastric primary choriocarcinoma and adenocarcinoma",
abstract = "Choriocarcinomas are commonly gestational and intrauterine or gonadal in origin. Nongestational and extragonadal disease, especially in the stomach is extremely rare with a poorer prognosis and early metastasis. We herein describe a case of primary gastric choriocarcinoma with liver metastasis in a 69-year-old male. The patient presented with abdominal pain and irregular bowel habits of one month duration. Both endoscopic and radiographic imaging revealed an ulcerated and necrotic circumferential tumor in the pyloric antrum of the stomach. The histopathologic findings of the resected tumor were that of an extensively necrotic and hemorrhagic neoplasm with combined choriocarcinomatous and adenocarcinomatous element. A strongly positive immunohistochemical staining for - subunit of human chorionic gonadotropin (-HCG) in the choriocarcinomatous component and a proper correlation with elevated serum -HCG levels confirmed the diagnosis.",
author = "Pai, {Muktha R.} and Mathai, {Alka M.} and Suneet Kumar and Shivananda Prabhu",
year = "2009",
month = "10",
day = "1",
doi = "10.4103/0377-4929.56155",
language = "English",
volume = "52",
pages = "537--539",
journal = "Indian Journal of Pathology and Microbiology",
issn = "0377-4929",
publisher = "Medknow Publications and Media Pvt. Ltd",
number = "4",

}

Coexistent gastric primary choriocarcinoma and adenocarcinoma. / Pai, Muktha R.; Mathai, Alka M.; Kumar, Suneet; Prabhu, Shivananda.

In: Indian Journal of Pathology and Microbiology, Vol. 52, No. 4, 01.10.2009, p. 537-539.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Coexistent gastric primary choriocarcinoma and adenocarcinoma

AU - Pai, Muktha R.

AU - Mathai, Alka M.

AU - Kumar, Suneet

AU - Prabhu, Shivananda

PY - 2009/10/1

Y1 - 2009/10/1

N2 - Choriocarcinomas are commonly gestational and intrauterine or gonadal in origin. Nongestational and extragonadal disease, especially in the stomach is extremely rare with a poorer prognosis and early metastasis. We herein describe a case of primary gastric choriocarcinoma with liver metastasis in a 69-year-old male. The patient presented with abdominal pain and irregular bowel habits of one month duration. Both endoscopic and radiographic imaging revealed an ulcerated and necrotic circumferential tumor in the pyloric antrum of the stomach. The histopathologic findings of the resected tumor were that of an extensively necrotic and hemorrhagic neoplasm with combined choriocarcinomatous and adenocarcinomatous element. A strongly positive immunohistochemical staining for - subunit of human chorionic gonadotropin (-HCG) in the choriocarcinomatous component and a proper correlation with elevated serum -HCG levels confirmed the diagnosis.

AB - Choriocarcinomas are commonly gestational and intrauterine or gonadal in origin. Nongestational and extragonadal disease, especially in the stomach is extremely rare with a poorer prognosis and early metastasis. We herein describe a case of primary gastric choriocarcinoma with liver metastasis in a 69-year-old male. The patient presented with abdominal pain and irregular bowel habits of one month duration. Both endoscopic and radiographic imaging revealed an ulcerated and necrotic circumferential tumor in the pyloric antrum of the stomach. The histopathologic findings of the resected tumor were that of an extensively necrotic and hemorrhagic neoplasm with combined choriocarcinomatous and adenocarcinomatous element. A strongly positive immunohistochemical staining for - subunit of human chorionic gonadotropin (-HCG) in the choriocarcinomatous component and a proper correlation with elevated serum -HCG levels confirmed the diagnosis.

UR - http://www.scopus.com/inward/record.url?scp=70350327590&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70350327590&partnerID=8YFLogxK

U2 - 10.4103/0377-4929.56155

DO - 10.4103/0377-4929.56155

M3 - Article

VL - 52

SP - 537

EP - 539

JO - Indian Journal of Pathology and Microbiology

JF - Indian Journal of Pathology and Microbiology

SN - 0377-4929

IS - 4

ER -