Cognitive dysfunction among adults with type 2 diabetes mellitus in Karnataka, India

Devesh Bhaskar Yerrapragada, Chythra R. Rao, Kavinya Karunakaran, Henry Seow Ern Lee

Research output: Contribution to journalArticle

Abstract

Background: Type 2 diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia that affects various body systems. Elevated blood glucose levels cause brain malfunction, sorbitol-induced blood vessel damage, and degeneration of the nerves that can lead to dementia or cognitive impairment. Cognitive impairment can result in nonadherence of patients to diabetes treatment, such as diet, medication, and exercise. Methods:We used a cross-sectional design to individually interview 194 patients with type 2 diabetes in a rural field practice area in India. A questionnaire was used to collect sociodemographic and diabetes disease characteristics; anthropometric measurements were also collected. Cognitive dysfunction was assessed with the Kannada version (local language) of the Montreal Cognitive Assessment (MoCA) tool. Blood pressure wasmeasured for all subjects using a standardized sphygmomanometer on the right arm with the patient in a sitting position. Results: Amongthe 194 diabetic subjects interviewed, 98 (50.5%) were cognitively impaired. More than half of the subjects (56.2%) were ≥65 years, and female participants (53.6%) outnumbered males (46.4%). The majority of patients (62.4%) had had diabetes for<10 years. The sociodemographic characteristics age, sex, education, occupation, and socioeconomic status and the anthropometric measurement ofwaist-to-hip ratiowere significantly associated (P<0.05) with cognitive impairment.Disease characteristics, religion, and blood pressure showed no significant association with cognitive impairment. Conclusion: One in two individuals with type 2 diabetes mellitus in our study population had mild cognitive impairment. Older individuals in the low socioeconomic strata and with low levels of education were identified to be at high risk of cognitive impairment. Hence, screening and appropriate care need to be provided.

Original languageEnglish
Pages (from-to)227-234
Number of pages8
JournalOchsner Journal
Volume19
Issue number3
DOIs
Publication statusPublished - 01-09-2019

Fingerprint

Type 2 Diabetes Mellitus
India
Sphygmomanometers
Blood Pressure
Nerve Degeneration
Sex Education
Sorbitol
Metabolic Diseases
Religion
Patient Compliance
Cognitive Dysfunction
Posture
Occupations
Social Class
Hyperglycemia
Blood Vessels
Dementia
Blood Glucose
Hip
Arm

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Yerrapragada, Devesh Bhaskar ; Rao, Chythra R. ; Karunakaran, Kavinya ; Lee, Henry Seow Ern. / Cognitive dysfunction among adults with type 2 diabetes mellitus in Karnataka, India. In: Ochsner Journal. 2019 ; Vol. 19, No. 3. pp. 227-234.
@article{92c8340ad1ca40978065c6e68321a6ac,
title = "Cognitive dysfunction among adults with type 2 diabetes mellitus in Karnataka, India",
abstract = "Background: Type 2 diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia that affects various body systems. Elevated blood glucose levels cause brain malfunction, sorbitol-induced blood vessel damage, and degeneration of the nerves that can lead to dementia or cognitive impairment. Cognitive impairment can result in nonadherence of patients to diabetes treatment, such as diet, medication, and exercise. Methods:We used a cross-sectional design to individually interview 194 patients with type 2 diabetes in a rural field practice area in India. A questionnaire was used to collect sociodemographic and diabetes disease characteristics; anthropometric measurements were also collected. Cognitive dysfunction was assessed with the Kannada version (local language) of the Montreal Cognitive Assessment (MoCA) tool. Blood pressure wasmeasured for all subjects using a standardized sphygmomanometer on the right arm with the patient in a sitting position. Results: Amongthe 194 diabetic subjects interviewed, 98 (50.5{\%}) were cognitively impaired. More than half of the subjects (56.2{\%}) were ≥65 years, and female participants (53.6{\%}) outnumbered males (46.4{\%}). The majority of patients (62.4{\%}) had had diabetes for<10 years. The sociodemographic characteristics age, sex, education, occupation, and socioeconomic status and the anthropometric measurement ofwaist-to-hip ratiowere significantly associated (P<0.05) with cognitive impairment.Disease characteristics, religion, and blood pressure showed no significant association with cognitive impairment. Conclusion: One in two individuals with type 2 diabetes mellitus in our study population had mild cognitive impairment. Older individuals in the low socioeconomic strata and with low levels of education were identified to be at high risk of cognitive impairment. Hence, screening and appropriate care need to be provided.",
author = "Yerrapragada, {Devesh Bhaskar} and Rao, {Chythra R.} and Kavinya Karunakaran and Lee, {Henry Seow Ern}",
year = "2019",
month = "9",
day = "1",
doi = "10.31486/toj.18.0160",
language = "English",
volume = "19",
pages = "227--234",
journal = "Ochsner Journal",
issn = "1524-5012",
publisher = "Ochsner Clinic",
number = "3",

}

Cognitive dysfunction among adults with type 2 diabetes mellitus in Karnataka, India. / Yerrapragada, Devesh Bhaskar; Rao, Chythra R.; Karunakaran, Kavinya; Lee, Henry Seow Ern.

In: Ochsner Journal, Vol. 19, No. 3, 01.09.2019, p. 227-234.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cognitive dysfunction among adults with type 2 diabetes mellitus in Karnataka, India

AU - Yerrapragada, Devesh Bhaskar

AU - Rao, Chythra R.

AU - Karunakaran, Kavinya

AU - Lee, Henry Seow Ern

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Background: Type 2 diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia that affects various body systems. Elevated blood glucose levels cause brain malfunction, sorbitol-induced blood vessel damage, and degeneration of the nerves that can lead to dementia or cognitive impairment. Cognitive impairment can result in nonadherence of patients to diabetes treatment, such as diet, medication, and exercise. Methods:We used a cross-sectional design to individually interview 194 patients with type 2 diabetes in a rural field practice area in India. A questionnaire was used to collect sociodemographic and diabetes disease characteristics; anthropometric measurements were also collected. Cognitive dysfunction was assessed with the Kannada version (local language) of the Montreal Cognitive Assessment (MoCA) tool. Blood pressure wasmeasured for all subjects using a standardized sphygmomanometer on the right arm with the patient in a sitting position. Results: Amongthe 194 diabetic subjects interviewed, 98 (50.5%) were cognitively impaired. More than half of the subjects (56.2%) were ≥65 years, and female participants (53.6%) outnumbered males (46.4%). The majority of patients (62.4%) had had diabetes for<10 years. The sociodemographic characteristics age, sex, education, occupation, and socioeconomic status and the anthropometric measurement ofwaist-to-hip ratiowere significantly associated (P<0.05) with cognitive impairment.Disease characteristics, religion, and blood pressure showed no significant association with cognitive impairment. Conclusion: One in two individuals with type 2 diabetes mellitus in our study population had mild cognitive impairment. Older individuals in the low socioeconomic strata and with low levels of education were identified to be at high risk of cognitive impairment. Hence, screening and appropriate care need to be provided.

AB - Background: Type 2 diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia that affects various body systems. Elevated blood glucose levels cause brain malfunction, sorbitol-induced blood vessel damage, and degeneration of the nerves that can lead to dementia or cognitive impairment. Cognitive impairment can result in nonadherence of patients to diabetes treatment, such as diet, medication, and exercise. Methods:We used a cross-sectional design to individually interview 194 patients with type 2 diabetes in a rural field practice area in India. A questionnaire was used to collect sociodemographic and diabetes disease characteristics; anthropometric measurements were also collected. Cognitive dysfunction was assessed with the Kannada version (local language) of the Montreal Cognitive Assessment (MoCA) tool. Blood pressure wasmeasured for all subjects using a standardized sphygmomanometer on the right arm with the patient in a sitting position. Results: Amongthe 194 diabetic subjects interviewed, 98 (50.5%) were cognitively impaired. More than half of the subjects (56.2%) were ≥65 years, and female participants (53.6%) outnumbered males (46.4%). The majority of patients (62.4%) had had diabetes for<10 years. The sociodemographic characteristics age, sex, education, occupation, and socioeconomic status and the anthropometric measurement ofwaist-to-hip ratiowere significantly associated (P<0.05) with cognitive impairment.Disease characteristics, religion, and blood pressure showed no significant association with cognitive impairment. Conclusion: One in two individuals with type 2 diabetes mellitus in our study population had mild cognitive impairment. Older individuals in the low socioeconomic strata and with low levels of education were identified to be at high risk of cognitive impairment. Hence, screening and appropriate care need to be provided.

UR - http://www.scopus.com/inward/record.url?scp=85073473148&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85073473148&partnerID=8YFLogxK

U2 - 10.31486/toj.18.0160

DO - 10.31486/toj.18.0160

M3 - Article

AN - SCOPUS:85073473148

VL - 19

SP - 227

EP - 234

JO - Ochsner Journal

JF - Ochsner Journal

SN - 1524-5012

IS - 3

ER -