Coinfection of leprosy and tuberculosis

Seema Shetty, Shashikiran Umakanth, Bhawani Manandhar, Pankaj Bahadur Nepali

Research output: Contribution to journalArticle

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Abstract

Leprosy and tuberculosis (TB) are endemic to India, however, their coinfection is not frequently encountered in clinical practice. Here, we report a 32-year-old female patient who presented with a history of high-grade intermittent fever, cough and painless skin lesions since a month, along with bilateral claw hand (on examination). The haematological profile was suggestive of anaemia of chronic disease, chest radiograph showed consolidation, sputum smears were positive for Mycobacterium tuberculosis, and skin slit smear confirmed leprosy. The patient was prescribed WHO recommended multidrug therapy for multibacillary leprosy with three drugs. Additionally, prednisolone was added to her regimen for 2 weeks to treat the type 2 lepra reaction. For treatment of TB, she was placed on the standard 6-month short course chemotherapy. She was lost to follow-up, and attempts were made to contact her. Later, it came to our notice that she had discontinued medications and passed away 3 months after diagnosis.

Original languageEnglish
Article number222352
JournalBMJ Case Reports
Volume2018
DOIs
Publication statusPublished - 01-01-2018

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Leprosy
Coinfection
Tuberculosis
Multibacillary Leprosy
Hoof and Claw
Skin
Lost to Follow-Up
Prednisolone
Sputum
Mycobacterium tuberculosis
Cough
Anemia
India
Chronic Disease
Fever
Thorax
Hand
Drug Therapy
Therapeutics
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Shetty, Seema ; Umakanth, Shashikiran ; Manandhar, Bhawani ; Nepali, Pankaj Bahadur. / Coinfection of leprosy and tuberculosis. In: BMJ Case Reports. 2018 ; Vol. 2018.
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Coinfection of leprosy and tuberculosis. / Shetty, Seema; Umakanth, Shashikiran; Manandhar, Bhawani; Nepali, Pankaj Bahadur.

In: BMJ Case Reports, Vol. 2018, 222352, 01.01.2018.

Research output: Contribution to journalArticle

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AU - Shetty, Seema

AU - Umakanth, Shashikiran

AU - Manandhar, Bhawani

AU - Nepali, Pankaj Bahadur

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AB - Leprosy and tuberculosis (TB) are endemic to India, however, their coinfection is not frequently encountered in clinical practice. Here, we report a 32-year-old female patient who presented with a history of high-grade intermittent fever, cough and painless skin lesions since a month, along with bilateral claw hand (on examination). The haematological profile was suggestive of anaemia of chronic disease, chest radiograph showed consolidation, sputum smears were positive for Mycobacterium tuberculosis, and skin slit smear confirmed leprosy. The patient was prescribed WHO recommended multidrug therapy for multibacillary leprosy with three drugs. Additionally, prednisolone was added to her regimen for 2 weeks to treat the type 2 lepra reaction. For treatment of TB, she was placed on the standard 6-month short course chemotherapy. She was lost to follow-up, and attempts were made to contact her. Later, it came to our notice that she had discontinued medications and passed away 3 months after diagnosis.

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