Colorectal cancer and its risk factors among patients attending a tertiary care hospital in Southern Karnataka, India

Rashmi R. Aithal, Ranjitha S. Shetty, V. S. Binu, Sneha Deepak Mallya, K. Rajgopal Shenoy, Suma Nair

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: The objective of this study is to determine the association between certain sociodemographic and lifestyle factors with colorectal cancer. Methods: This case–control study was conducted using a pre-designed questionnaire among 100 incident colorectal cancer patients and 200 unmatched controls attending a Tertiary Care Hospital in Southern Karnataka. Cases and the controls were interviewed, and details regarding their sociodemographic factors were collected. Information on lifestyle factors such as dietary habits, physical activity levels, and substance use were documented. They were also assessed for the presence of existing comorbidities and family history of colorectal and other cancers. Multivariable logistic regression was performed to determine the association between various risk factors and colorectal cancer. Results: In the present hospital-based study, mean age of the participants was <55 years. About 63% of the cases and 54.5% of the controls were males. On multivariable analysis, age ≥50 years (odds ratio [OR]=1.87; 95% confidence interval [CI]=1.02-3.45), low physical activity (OR=5.66; 95% CI=3.10-10.34) and low frequency of fruits consumption (OR=4.10; 95% CI=2.21-7.50), and hypertension (OR=4.65; 95% CI=1.32-16.44) showed a positive association with colorectal cancer. Conclusion: Promoting healthy dietary practices and physical activity among the middle-aged population appears to be significant in the context of colorectal cancer prevention in the Indian subcontinent.

Original languageEnglish
Pages (from-to)109-112
Number of pages4
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume10
Issue number4
DOIs
Publication statusPublished - 01-04-2017

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Tertiary Healthcare
Tertiary Care Centers
India
Colorectal Neoplasms
Odds Ratio
Confidence Intervals
Exercise
Life Style
Feeding Behavior
Comorbidity
Fruit
Logistic Models
Hypertension
Population

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Pharmacology (medical)

Cite this

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title = "Colorectal cancer and its risk factors among patients attending a tertiary care hospital in Southern Karnataka, India",
abstract = "Objective: The objective of this study is to determine the association between certain sociodemographic and lifestyle factors with colorectal cancer. Methods: This case–control study was conducted using a pre-designed questionnaire among 100 incident colorectal cancer patients and 200 unmatched controls attending a Tertiary Care Hospital in Southern Karnataka. Cases and the controls were interviewed, and details regarding their sociodemographic factors were collected. Information on lifestyle factors such as dietary habits, physical activity levels, and substance use were documented. They were also assessed for the presence of existing comorbidities and family history of colorectal and other cancers. Multivariable logistic regression was performed to determine the association between various risk factors and colorectal cancer. Results: In the present hospital-based study, mean age of the participants was <55 years. About 63{\%} of the cases and 54.5{\%} of the controls were males. On multivariable analysis, age ≥50 years (odds ratio [OR]=1.87; 95{\%} confidence interval [CI]=1.02-3.45), low physical activity (OR=5.66; 95{\%} CI=3.10-10.34) and low frequency of fruits consumption (OR=4.10; 95{\%} CI=2.21-7.50), and hypertension (OR=4.65; 95{\%} CI=1.32-16.44) showed a positive association with colorectal cancer. Conclusion: Promoting healthy dietary practices and physical activity among the middle-aged population appears to be significant in the context of colorectal cancer prevention in the Indian subcontinent.",
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Colorectal cancer and its risk factors among patients attending a tertiary care hospital in Southern Karnataka, India. / Aithal, Rashmi R.; Shetty, Ranjitha S.; Binu, V. S.; Mallya, Sneha Deepak; Rajgopal Shenoy, K.; Nair, Suma.

In: Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, No. 4, 01.04.2017, p. 109-112.

Research output: Contribution to journalArticle

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T1 - Colorectal cancer and its risk factors among patients attending a tertiary care hospital in Southern Karnataka, India

AU - Aithal, Rashmi R.

AU - Shetty, Ranjitha S.

AU - Binu, V. S.

AU - Mallya, Sneha Deepak

AU - Rajgopal Shenoy, K.

AU - Nair, Suma

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N2 - Objective: The objective of this study is to determine the association between certain sociodemographic and lifestyle factors with colorectal cancer. Methods: This case–control study was conducted using a pre-designed questionnaire among 100 incident colorectal cancer patients and 200 unmatched controls attending a Tertiary Care Hospital in Southern Karnataka. Cases and the controls were interviewed, and details regarding their sociodemographic factors were collected. Information on lifestyle factors such as dietary habits, physical activity levels, and substance use were documented. They were also assessed for the presence of existing comorbidities and family history of colorectal and other cancers. Multivariable logistic regression was performed to determine the association between various risk factors and colorectal cancer. Results: In the present hospital-based study, mean age of the participants was <55 years. About 63% of the cases and 54.5% of the controls were males. On multivariable analysis, age ≥50 years (odds ratio [OR]=1.87; 95% confidence interval [CI]=1.02-3.45), low physical activity (OR=5.66; 95% CI=3.10-10.34) and low frequency of fruits consumption (OR=4.10; 95% CI=2.21-7.50), and hypertension (OR=4.65; 95% CI=1.32-16.44) showed a positive association with colorectal cancer. Conclusion: Promoting healthy dietary practices and physical activity among the middle-aged population appears to be significant in the context of colorectal cancer prevention in the Indian subcontinent.

AB - Objective: The objective of this study is to determine the association between certain sociodemographic and lifestyle factors with colorectal cancer. Methods: This case–control study was conducted using a pre-designed questionnaire among 100 incident colorectal cancer patients and 200 unmatched controls attending a Tertiary Care Hospital in Southern Karnataka. Cases and the controls were interviewed, and details regarding their sociodemographic factors were collected. Information on lifestyle factors such as dietary habits, physical activity levels, and substance use were documented. They were also assessed for the presence of existing comorbidities and family history of colorectal and other cancers. Multivariable logistic regression was performed to determine the association between various risk factors and colorectal cancer. Results: In the present hospital-based study, mean age of the participants was <55 years. About 63% of the cases and 54.5% of the controls were males. On multivariable analysis, age ≥50 years (odds ratio [OR]=1.87; 95% confidence interval [CI]=1.02-3.45), low physical activity (OR=5.66; 95% CI=3.10-10.34) and low frequency of fruits consumption (OR=4.10; 95% CI=2.21-7.50), and hypertension (OR=4.65; 95% CI=1.32-16.44) showed a positive association with colorectal cancer. Conclusion: Promoting healthy dietary practices and physical activity among the middle-aged population appears to be significant in the context of colorectal cancer prevention in the Indian subcontinent.

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