Combined neuroendocrine small cell carcinoma of trachea with crescentic glomerulonephritis as a paraneoplastic manifestation

Waqas Wahid Baig, Ravindra Prabhu Attur, Srikanth Gundlapalli, G. Karanam, Lakshmi Rao, Manna Valiathan

Research output: Contribution to journalArticle

Abstract

A middle aged female presented with history of breathlessness and swelling of legs of 2 weeks duration; the clinical and laboratory picture was suggestive of rapidly progressive renal failure and the kidney biopsy revealed a crescentic glomerulonephritis. Her renal function improved with the steroid therapy; in view of persistent breathlessness despite good diuresis chest radiograph was repeated which showed reduced lung volume on right and compensatory emphysema on the left side; a computerized tomography (CT) scan of the thorax showed a mass lesion partially obliterating the right main bronchial lumen. The mass on histopathology revealed small cell neuroendocrine carcinoma (SCNC) with adenosquamous carcinoma. To our knowledge only one case of neuroendocrine tumor presenting as a crescentic glomerulonephritis has been reported in the literature.

Original languageEnglish
Pages (from-to)228-230
Number of pages3
JournalRespiratory Medicine CME
Volume1
Issue number3
DOIs
Publication statusPublished - 25-09-2008

Fingerprint

Neuroendocrine Carcinoma
Neuroendocrine Cells
Small Cell Carcinoma
Glomerulonephritis
Trachea
Dyspnea
Thorax
Adenosquamous Carcinoma
Kidney
Neuroendocrine Tumors
Diuresis
Emphysema
Renal Insufficiency
Leg
Steroids
Tomography
Biopsy
Lung
Therapeutics

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cite this

@article{77cbe6bc22fe4d839b69669d29dc600e,
title = "Combined neuroendocrine small cell carcinoma of trachea with crescentic glomerulonephritis as a paraneoplastic manifestation",
abstract = "A middle aged female presented with history of breathlessness and swelling of legs of 2 weeks duration; the clinical and laboratory picture was suggestive of rapidly progressive renal failure and the kidney biopsy revealed a crescentic glomerulonephritis. Her renal function improved with the steroid therapy; in view of persistent breathlessness despite good diuresis chest radiograph was repeated which showed reduced lung volume on right and compensatory emphysema on the left side; a computerized tomography (CT) scan of the thorax showed a mass lesion partially obliterating the right main bronchial lumen. The mass on histopathology revealed small cell neuroendocrine carcinoma (SCNC) with adenosquamous carcinoma. To our knowledge only one case of neuroendocrine tumor presenting as a crescentic glomerulonephritis has been reported in the literature.",
author = "Baig, {Waqas Wahid} and Attur, {Ravindra Prabhu} and Srikanth Gundlapalli and G. Karanam and Lakshmi Rao and Manna Valiathan",
year = "2008",
month = "9",
day = "25",
doi = "10.1016/j.rmedc.2008.07.012",
language = "English",
volume = "1",
pages = "228--230",
journal = "Respiratory Medicine Case Reports",
issn = "2213-0071",
publisher = "Elsevier BV",
number = "3",

}

Combined neuroendocrine small cell carcinoma of trachea with crescentic glomerulonephritis as a paraneoplastic manifestation. / Baig, Waqas Wahid; Attur, Ravindra Prabhu; Gundlapalli, Srikanth; Karanam, G.; Rao, Lakshmi; Valiathan, Manna.

In: Respiratory Medicine CME, Vol. 1, No. 3, 25.09.2008, p. 228-230.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Combined neuroendocrine small cell carcinoma of trachea with crescentic glomerulonephritis as a paraneoplastic manifestation

AU - Baig, Waqas Wahid

AU - Attur, Ravindra Prabhu

AU - Gundlapalli, Srikanth

AU - Karanam, G.

AU - Rao, Lakshmi

AU - Valiathan, Manna

PY - 2008/9/25

Y1 - 2008/9/25

N2 - A middle aged female presented with history of breathlessness and swelling of legs of 2 weeks duration; the clinical and laboratory picture was suggestive of rapidly progressive renal failure and the kidney biopsy revealed a crescentic glomerulonephritis. Her renal function improved with the steroid therapy; in view of persistent breathlessness despite good diuresis chest radiograph was repeated which showed reduced lung volume on right and compensatory emphysema on the left side; a computerized tomography (CT) scan of the thorax showed a mass lesion partially obliterating the right main bronchial lumen. The mass on histopathology revealed small cell neuroendocrine carcinoma (SCNC) with adenosquamous carcinoma. To our knowledge only one case of neuroendocrine tumor presenting as a crescentic glomerulonephritis has been reported in the literature.

AB - A middle aged female presented with history of breathlessness and swelling of legs of 2 weeks duration; the clinical and laboratory picture was suggestive of rapidly progressive renal failure and the kidney biopsy revealed a crescentic glomerulonephritis. Her renal function improved with the steroid therapy; in view of persistent breathlessness despite good diuresis chest radiograph was repeated which showed reduced lung volume on right and compensatory emphysema on the left side; a computerized tomography (CT) scan of the thorax showed a mass lesion partially obliterating the right main bronchial lumen. The mass on histopathology revealed small cell neuroendocrine carcinoma (SCNC) with adenosquamous carcinoma. To our knowledge only one case of neuroendocrine tumor presenting as a crescentic glomerulonephritis has been reported in the literature.

UR - http://www.scopus.com/inward/record.url?scp=52149089459&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=52149089459&partnerID=8YFLogxK

U2 - 10.1016/j.rmedc.2008.07.012

DO - 10.1016/j.rmedc.2008.07.012

M3 - Article

VL - 1

SP - 228

EP - 230

JO - Respiratory Medicine Case Reports

JF - Respiratory Medicine Case Reports

SN - 2213-0071

IS - 3

ER -