Vergleichende Darstellung bisheriger ökonomischer Evaluationsstudien zum Screening auf Phenylketonurie

Translated title of the contribution: Comparative presentation of economic evaluation studies of phenylketoneuria screening

D. Ahrens, B. Güntert, A. Brand

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    A systematic review was undertaken to assess the economic value of PKU screening in the framework of newborn screening for inborn errors of metabolism. Therefore, seven international studies on this topic were connected and examined with regard to differences and similarities. The relation between costs and benefits of PKU-screening programmes goes from 1:1,2 up to 1:9,25. The differences can be explained by varying incidence of PKU (in international comparison) and particularly by methodical differences in the respective study designs. This aspect is pointed out while taking up and emphasising the necessity of standardisation in economic evaluation studies. Furthermore, future developments (chances, trends, changes) in newborn screening are discussed, based on the potential use of new technologies.

    Original languageGerman
    Pages (from-to)190-196
    Number of pages7
    JournalGesundheitswesen
    Volume61
    Issue number4
    Publication statusPublished - 01-12-1999

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    Cost-Benefit Analysis
    Inborn Errors Metabolism
    Economics
    Technology
    Incidence

    All Science Journal Classification (ASJC) codes

    • Public Health, Environmental and Occupational Health

    Cite this

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    title = "Vergleichende Darstellung bisheriger {\"o}konomischer Evaluationsstudien zum Screening auf Phenylketonurie",
    abstract = "A systematic review was undertaken to assess the economic value of PKU screening in the framework of newborn screening for inborn errors of metabolism. Therefore, seven international studies on this topic were connected and examined with regard to differences and similarities. The relation between costs and benefits of PKU-screening programmes goes from 1:1,2 up to 1:9,25. The differences can be explained by varying incidence of PKU (in international comparison) and particularly by methodical differences in the respective study designs. This aspect is pointed out while taking up and emphasising the necessity of standardisation in economic evaluation studies. Furthermore, future developments (chances, trends, changes) in newborn screening are discussed, based on the potential use of new technologies.",
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    Vergleichende Darstellung bisheriger ökonomischer Evaluationsstudien zum Screening auf Phenylketonurie. / Ahrens, D.; Güntert, B.; Brand, A.

    In: Gesundheitswesen, Vol. 61, No. 4, 01.12.1999, p. 190-196.

    Research output: Contribution to journalArticle

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