Comparson of the methods of diagnosis of bacterial vaginosis

Udayalaxm, Gopalkrishna Bhat, Subbannayya Kotigadde, Shalini Shenoy

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background and Objective: Although Nugent's criterion is considered as the gold standard, routinely a combination of various methods is used for the diagnosis of bacterial vaginosis. In the present study we compared culture, Spiegel's criteria and Amsel's criteria with Nugent's method for the diagnosis of bacterial vaginosis. Materials and Methods: Five hundred and twenty seven women who attended the Government Maternity Hospital and a tertiary care centre in south India for antenatal care or forany other complaint formed the study population. Diagnosis of bacterial vaginosis was done by culture, Amsel's, Nugent's and Spiegel's criteria. The positive predictive value, the negative predictive value and the sensitivity and specificity of these methods,in comparison with Nugent's criteria, by considering it as the gold standard, were calculated. Statistical analysis was done by using the Chi Square test or the Fisher's exact test as was appropriate. Results: In comparison with Nugent's criteria, the positive predictive value, negative predictive value and the sensitivity and specificity of Amsel's criteria were 80.4%, 94.8%, 78% and 95.6% and that of Spiegel's criteria were 77.5%, 100%, 100% and 93.2%. The culture was 51% sensitive and 88.7% specific, the positive predictive value was 85.5% and the negative predictive value was 58%. We diagnosed 100 (19%) casesof bacterial vaginosisby Nugent's method,129 (24%) casesby Spiegel's method,97 (18%) cases by Amsel's criteria and 88 (16.7%) cases by culturing. Conclusion: Amsel's and Spiegel's criteria were comparable with Nugent's criteria for the diagnosis of bacterial vaginosis. Diagnosis of bacterial vaginosis by culture was least sensitive method.

Original languageEnglish
Pages (from-to)498-501
Number of pages4
JournalJournal of Clinical and Diagnostic Research
Volume5
Issue number3
Publication statusPublished - 2011

Fingerprint

Bacterial Vaginosis
Sensitivity and Specificity
Maternity Hospitals
Prenatal Care
Statistical methods
Chi-Square Distribution
Tertiary Care Centers
India
Population

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Clinical Biochemistry

Cite this

@article{4edc5a099ca944ffa94d81b9a852d56a,
title = "Comparson of the methods of diagnosis of bacterial vaginosis",
abstract = "Background and Objective: Although Nugent's criterion is considered as the gold standard, routinely a combination of various methods is used for the diagnosis of bacterial vaginosis. In the present study we compared culture, Spiegel's criteria and Amsel's criteria with Nugent's method for the diagnosis of bacterial vaginosis. Materials and Methods: Five hundred and twenty seven women who attended the Government Maternity Hospital and a tertiary care centre in south India for antenatal care or forany other complaint formed the study population. Diagnosis of bacterial vaginosis was done by culture, Amsel's, Nugent's and Spiegel's criteria. The positive predictive value, the negative predictive value and the sensitivity and specificity of these methods,in comparison with Nugent's criteria, by considering it as the gold standard, were calculated. Statistical analysis was done by using the Chi Square test or the Fisher's exact test as was appropriate. Results: In comparison with Nugent's criteria, the positive predictive value, negative predictive value and the sensitivity and specificity of Amsel's criteria were 80.4{\%}, 94.8{\%}, 78{\%} and 95.6{\%} and that of Spiegel's criteria were 77.5{\%}, 100{\%}, 100{\%} and 93.2{\%}. The culture was 51{\%} sensitive and 88.7{\%} specific, the positive predictive value was 85.5{\%} and the negative predictive value was 58{\%}. We diagnosed 100 (19{\%}) casesof bacterial vaginosisby Nugent's method,129 (24{\%}) casesby Spiegel's method,97 (18{\%}) cases by Amsel's criteria and 88 (16.7{\%}) cases by culturing. Conclusion: Amsel's and Spiegel's criteria were comparable with Nugent's criteria for the diagnosis of bacterial vaginosis. Diagnosis of bacterial vaginosis by culture was least sensitive method.",
author = "Udayalaxm and Gopalkrishna Bhat and Subbannayya Kotigadde and Shalini Shenoy",
year = "2011",
language = "English",
volume = "5",
pages = "498--501",
journal = "Journal of Clinical and Diagnostic Research",
issn = "2249-782X",
publisher = "Journal of Clinical and Diagnostic Research",
number = "3",

}

Comparson of the methods of diagnosis of bacterial vaginosis. / Udayalaxm, ; Bhat, Gopalkrishna; Kotigadde, Subbannayya; Shenoy, Shalini.

In: Journal of Clinical and Diagnostic Research, Vol. 5, No. 3, 2011, p. 498-501.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Comparson of the methods of diagnosis of bacterial vaginosis

AU - Udayalaxm,

AU - Bhat, Gopalkrishna

AU - Kotigadde, Subbannayya

AU - Shenoy, Shalini

PY - 2011

Y1 - 2011

N2 - Background and Objective: Although Nugent's criterion is considered as the gold standard, routinely a combination of various methods is used for the diagnosis of bacterial vaginosis. In the present study we compared culture, Spiegel's criteria and Amsel's criteria with Nugent's method for the diagnosis of bacterial vaginosis. Materials and Methods: Five hundred and twenty seven women who attended the Government Maternity Hospital and a tertiary care centre in south India for antenatal care or forany other complaint formed the study population. Diagnosis of bacterial vaginosis was done by culture, Amsel's, Nugent's and Spiegel's criteria. The positive predictive value, the negative predictive value and the sensitivity and specificity of these methods,in comparison with Nugent's criteria, by considering it as the gold standard, were calculated. Statistical analysis was done by using the Chi Square test or the Fisher's exact test as was appropriate. Results: In comparison with Nugent's criteria, the positive predictive value, negative predictive value and the sensitivity and specificity of Amsel's criteria were 80.4%, 94.8%, 78% and 95.6% and that of Spiegel's criteria were 77.5%, 100%, 100% and 93.2%. The culture was 51% sensitive and 88.7% specific, the positive predictive value was 85.5% and the negative predictive value was 58%. We diagnosed 100 (19%) casesof bacterial vaginosisby Nugent's method,129 (24%) casesby Spiegel's method,97 (18%) cases by Amsel's criteria and 88 (16.7%) cases by culturing. Conclusion: Amsel's and Spiegel's criteria were comparable with Nugent's criteria for the diagnosis of bacterial vaginosis. Diagnosis of bacterial vaginosis by culture was least sensitive method.

AB - Background and Objective: Although Nugent's criterion is considered as the gold standard, routinely a combination of various methods is used for the diagnosis of bacterial vaginosis. In the present study we compared culture, Spiegel's criteria and Amsel's criteria with Nugent's method for the diagnosis of bacterial vaginosis. Materials and Methods: Five hundred and twenty seven women who attended the Government Maternity Hospital and a tertiary care centre in south India for antenatal care or forany other complaint formed the study population. Diagnosis of bacterial vaginosis was done by culture, Amsel's, Nugent's and Spiegel's criteria. The positive predictive value, the negative predictive value and the sensitivity and specificity of these methods,in comparison with Nugent's criteria, by considering it as the gold standard, were calculated. Statistical analysis was done by using the Chi Square test or the Fisher's exact test as was appropriate. Results: In comparison with Nugent's criteria, the positive predictive value, negative predictive value and the sensitivity and specificity of Amsel's criteria were 80.4%, 94.8%, 78% and 95.6% and that of Spiegel's criteria were 77.5%, 100%, 100% and 93.2%. The culture was 51% sensitive and 88.7% specific, the positive predictive value was 85.5% and the negative predictive value was 58%. We diagnosed 100 (19%) casesof bacterial vaginosisby Nugent's method,129 (24%) casesby Spiegel's method,97 (18%) cases by Amsel's criteria and 88 (16.7%) cases by culturing. Conclusion: Amsel's and Spiegel's criteria were comparable with Nugent's criteria for the diagnosis of bacterial vaginosis. Diagnosis of bacterial vaginosis by culture was least sensitive method.

UR - http://www.scopus.com/inward/record.url?scp=79959310915&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79959310915&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:79959310915

VL - 5

SP - 498

EP - 501

JO - Journal of Clinical and Diagnostic Research

JF - Journal of Clinical and Diagnostic Research

SN - 2249-782X

IS - 3

ER -