Complexation studies of norfloxacin with betacyclodextrin

K. S. Aithal, N. Udupa, K. K. Sreenivasan

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Norfloxacin (NOR) (1a) forms an inclusion complex with betacyclodextrin (BCD) (1c) by neutralisation method. The carboxyl function of norfloxacin is found to interact with the hydroxyl groups of betacyclodextrin present at the open end through hydrogen bonding as evidenced by spectral analysis.

Original languageEnglish
Pages (from-to)864-866
Number of pages3
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Volume35
Issue number8
Publication statusPublished - 08-1996

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Norfloxacin
Complexation
Hydrogen Bonding
Hydroxyl Radical
Spectrum analysis
Hydrogen bonds

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Organic Chemistry

Cite this

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Complexation studies of norfloxacin with betacyclodextrin. / Aithal, K. S.; Udupa, N.; Sreenivasan, K. K.

In: Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, Vol. 35, No. 8, 08.1996, p. 864-866.

Research output: Contribution to journalArticle

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T1 - Complexation studies of norfloxacin with betacyclodextrin

AU - Aithal, K. S.

AU - Udupa, N.

AU - Sreenivasan, K. K.

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N2 - Norfloxacin (NOR) (1a) forms an inclusion complex with betacyclodextrin (BCD) (1c) by neutralisation method. The carboxyl function of norfloxacin is found to interact with the hydroxyl groups of betacyclodextrin present at the open end through hydrogen bonding as evidenced by spectral analysis.

AB - Norfloxacin (NOR) (1a) forms an inclusion complex with betacyclodextrin (BCD) (1c) by neutralisation method. The carboxyl function of norfloxacin is found to interact with the hydroxyl groups of betacyclodextrin present at the open end through hydrogen bonding as evidenced by spectral analysis.

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