Complexation studies of norfloxacin with betacyclodextrin

K. S. Aithal, N. Udupa, K. K. Sreenivasan

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Abstract

Norfloxacin (NOR) (1a) forms an inclusion complex with betacyclodextrin (BCD) (1c) by neutralisation method. The carboxyl function of norfloxacin is found to interact with the hydroxyl groups of betacyclodextrin present at the open end through hydrogen bonding as evidenced by spectral analysis.

Original languageEnglish
Pages (from-to)864-866
Number of pages3
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Volume35
Issue number8
Publication statusPublished - 08-1996

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All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Organic Chemistry

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