Congenital scoliosis: An anomalous association with endosulfan

Jayakrishnan Kelamangalathu Narayana Kurup, Simanchal P. Mohanty

Research output: Contribution to journalArticle

Abstract

Endosulfan is an organochlorine pesticide that is used extensively across the world to kill insects. Incidence of acute and chronic toxicity with endosulfan poisoning has been reported, and nearly 80 countries have banned its use. However, it is still being used in many low-income/middle-income countries. One of the most severe tragedies because of endosulfan poisoning has taken place in the Indian state of Kerala due to persistent aerial spraying of endosulfan. Even though there are reports of skeletal and other congenital abnormalities in humans and experimental animals following exposure to endosulfan, very few have been documented. We report two cases of congenital scoliosis in siblings living in a community affected by high levels of endosulfan in the environment. High index of suspicion is essential during the screening of school children exposed to endosulfan. Congenital scoliosis is a progressive deformity that leads to severe disability, unless detected and corrected at an early stage.

Original languageEnglish
Article number220803
JournalBMJ Case Reports
Volume2017
DOIs
Publication statusPublished - 01-01-2017

Fingerprint

Endosulfan
Scoliosis
Poisoning
Pesticides
Insects
Siblings
Incidence

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Kurup, Jayakrishnan Kelamangalathu Narayana ; Mohanty, Simanchal P. / Congenital scoliosis : An anomalous association with endosulfan. In: BMJ Case Reports. 2017 ; Vol. 2017.
@article{08b76eac9b4d42ebb227e1f423c63412,
title = "Congenital scoliosis: An anomalous association with endosulfan",
abstract = "Endosulfan is an organochlorine pesticide that is used extensively across the world to kill insects. Incidence of acute and chronic toxicity with endosulfan poisoning has been reported, and nearly 80 countries have banned its use. However, it is still being used in many low-income/middle-income countries. One of the most severe tragedies because of endosulfan poisoning has taken place in the Indian state of Kerala due to persistent aerial spraying of endosulfan. Even though there are reports of skeletal and other congenital abnormalities in humans and experimental animals following exposure to endosulfan, very few have been documented. We report two cases of congenital scoliosis in siblings living in a community affected by high levels of endosulfan in the environment. High index of suspicion is essential during the screening of school children exposed to endosulfan. Congenital scoliosis is a progressive deformity that leads to severe disability, unless detected and corrected at an early stage.",
author = "Kurup, {Jayakrishnan Kelamangalathu Narayana} and Mohanty, {Simanchal P.}",
year = "2017",
month = "1",
day = "1",
doi = "10.1136/bcr-2017-220803",
language = "English",
volume = "2017",
journal = "BMJ Case Reports",
issn = "1757-790X",
publisher = "BMJ Publishing Group",

}

Congenital scoliosis : An anomalous association with endosulfan. / Kurup, Jayakrishnan Kelamangalathu Narayana; Mohanty, Simanchal P.

In: BMJ Case Reports, Vol. 2017, 220803, 01.01.2017.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Congenital scoliosis

T2 - An anomalous association with endosulfan

AU - Kurup, Jayakrishnan Kelamangalathu Narayana

AU - Mohanty, Simanchal P.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Endosulfan is an organochlorine pesticide that is used extensively across the world to kill insects. Incidence of acute and chronic toxicity with endosulfan poisoning has been reported, and nearly 80 countries have banned its use. However, it is still being used in many low-income/middle-income countries. One of the most severe tragedies because of endosulfan poisoning has taken place in the Indian state of Kerala due to persistent aerial spraying of endosulfan. Even though there are reports of skeletal and other congenital abnormalities in humans and experimental animals following exposure to endosulfan, very few have been documented. We report two cases of congenital scoliosis in siblings living in a community affected by high levels of endosulfan in the environment. High index of suspicion is essential during the screening of school children exposed to endosulfan. Congenital scoliosis is a progressive deformity that leads to severe disability, unless detected and corrected at an early stage.

AB - Endosulfan is an organochlorine pesticide that is used extensively across the world to kill insects. Incidence of acute and chronic toxicity with endosulfan poisoning has been reported, and nearly 80 countries have banned its use. However, it is still being used in many low-income/middle-income countries. One of the most severe tragedies because of endosulfan poisoning has taken place in the Indian state of Kerala due to persistent aerial spraying of endosulfan. Even though there are reports of skeletal and other congenital abnormalities in humans and experimental animals following exposure to endosulfan, very few have been documented. We report two cases of congenital scoliosis in siblings living in a community affected by high levels of endosulfan in the environment. High index of suspicion is essential during the screening of school children exposed to endosulfan. Congenital scoliosis is a progressive deformity that leads to severe disability, unless detected and corrected at an early stage.

UR - http://www.scopus.com/inward/record.url?scp=85038636586&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85038636586&partnerID=8YFLogxK

U2 - 10.1136/bcr-2017-220803

DO - 10.1136/bcr-2017-220803

M3 - Article

AN - SCOPUS:85038636586

VL - 2017

JO - BMJ Case Reports

JF - BMJ Case Reports

SN - 1757-790X

M1 - 220803

ER -