Controlled release of the drug cefadroxil from polycaprolactone-polylactic acid nanocomposites

Rashmirekha Sahoo, Sarmila Sahoo, Preetishree Nayak, Soumendra Sahoo, Padmalochan Nayak

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Two most important biodegradable polymers such as polycaprolactone and polylactic acid have been compounded in different proportions with organoclay MMT by melt blending.Organo clay MMT was added to enhance their compatibility and mechanical properties.The materials were characterized by using XRD, FTIR, thscanning electron microscopy, and thermogravimetric analysis.XRD results indicatedthat the materials formed intervcalated the nano composites.SEM morphology showed that the increasing content of MMT reduces the domain size of phase separated particles.The controlled drug delivery system has been studied using these bionanocomposites as the carrier. The kinetic parameters have been evaluated and the drug delivery mechanism has been suggested.

Original languageEnglish
Pages (from-to)154-162
Number of pages9
JournalEuropean Journal of Scientific Research
Volume53
Issue number2
Publication statusPublished - 01-01-2011
Externally publishedYes

Fingerprint

Cefadroxil
polylactic acid
organoclay
nanocomposites
Nanocomposites
Polycaprolactone
Organoclay
Drug Delivery
Drugs
drug
X-ray diffraction
Controlled drug delivery
thermogravimetry
drug delivery systems
drugs
biodegradability
Biodegradable polymers
Acids
acid
Electron Microscopy

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Mathematics(all)
  • Materials Science(all)
  • Agricultural and Biological Sciences(all)
  • Engineering(all)
  • Earth and Planetary Sciences(all)

Cite this

Sahoo, Rashmirekha ; Sahoo, Sarmila ; Nayak, Preetishree ; Sahoo, Soumendra ; Nayak, Padmalochan. / Controlled release of the drug cefadroxil from polycaprolactone-polylactic acid nanocomposites. In: European Journal of Scientific Research. 2011 ; Vol. 53, No. 2. pp. 154-162.
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Sahoo, R, Sahoo, S, Nayak, P, Sahoo, S & Nayak, P 2011, 'Controlled release of the drug cefadroxil from polycaprolactone-polylactic acid nanocomposites', European Journal of Scientific Research, vol. 53, no. 2, pp. 154-162.

Controlled release of the drug cefadroxil from polycaprolactone-polylactic acid nanocomposites. / Sahoo, Rashmirekha; Sahoo, Sarmila; Nayak, Preetishree; Sahoo, Soumendra; Nayak, Padmalochan.

In: European Journal of Scientific Research, Vol. 53, No. 2, 01.01.2011, p. 154-162.

Research output: Contribution to journalArticle

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