TY - JOUR
T1 - Correlation between neutrophil-lymphocyte ratio and proteinuria in diabetes
AU - Shetty, Meenakshi
AU - Hussain, Mohammed Ahmed
AU - Jeganathan, Jayakumar
AU - M R, Pavan
PY - 2019/10
Y1 - 2019/10
N2 - Introduction: To study the relationship between Neutrophil-lymphocyte ratio and proteinuria in diabetes. Materials and Method: This was a cross sectional study 196 diabetic subjects. They were divided into no nephropathy, incipient nephropathy and overt nephropathy. The Neutrophil lymphocyte ratio was compared between the three groups using Mann Whitney U test. Pearsons correlation was used to compare the other parameters between the three groups. Results: There was significant difference between the median Neutrophil lymphocyte ratios in the three groups. The median NLR in patients with ‘no nephropathy’ was 2.69 (1.64-2.53). In patients with ‘incipient nephropathy’ was 2.77 (1.81-4.65). In patients with ‘overt nephropathy’ was 3.77 (2.01-5.39). A value of 2.752 of NLR can be taken as a cut off for predicting Overt Nephropathy with 74% sensitivity and 50% specificity. Conclusion: Being a commonly available and cheap test, NLR can be advocated as a useful screening test in diabetics to predict the development or presence of diabetic nephropathy.
AB - Introduction: To study the relationship between Neutrophil-lymphocyte ratio and proteinuria in diabetes. Materials and Method: This was a cross sectional study 196 diabetic subjects. They were divided into no nephropathy, incipient nephropathy and overt nephropathy. The Neutrophil lymphocyte ratio was compared between the three groups using Mann Whitney U test. Pearsons correlation was used to compare the other parameters between the three groups. Results: There was significant difference between the median Neutrophil lymphocyte ratios in the three groups. The median NLR in patients with ‘no nephropathy’ was 2.69 (1.64-2.53). In patients with ‘incipient nephropathy’ was 2.77 (1.81-4.65). In patients with ‘overt nephropathy’ was 3.77 (2.01-5.39). A value of 2.752 of NLR can be taken as a cut off for predicting Overt Nephropathy with 74% sensitivity and 50% specificity. Conclusion: Being a commonly available and cheap test, NLR can be advocated as a useful screening test in diabetics to predict the development or presence of diabetic nephropathy.
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U2 - 10.5958/0976-5506.2019.02772.4
DO - 10.5958/0976-5506.2019.02772.4
M3 - Article
VL - 10
SP - 80
EP - 82
JO - Indian Journal of Public Health Research and Development
JF - Indian Journal of Public Health Research and Development
SN - 0976-0245
IS - 10
ER -
