Correlation of CD4 cell count with gingival bleeding index in HIV positive individuals

Dolar Doshi, John T. Ramapuram, N. Anup, Gaurav Sharma

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Abstract

Objectives: To correlate CD4 cell count with gingival bleeding index in HIV positive individuals. Methods: Fifty-one serologically confirmed HIV positive individuals were included in the study. Plaque index and bleeding index was recorded by a single examiner. CD4 cell count was obtained within 30 days from the day of examination. CD4 cell counts and gingival bleeding index was correlated using Spearman's correlation test. p < 0.01 was considered as statistically significant. Results: Mean plaque score, mean gingival bleeding index score and mean CD4 cell count was 1.40, 0.96 and 249.86 cells/mm 3 respectively. It was noticed that gingival bleeding was enhanced in individuals with increased immunosuppression. However, no significant positive correlation was seen between mean CD4 cell count and gingival bleeding (p = 0.14). Conclusion: Though CD4 cells are an important indicator for clinical aggravation of HIV infection, periodontal disease as measured by bleeding index is not directly associated to the cell count.

Original languageEnglish
Article number1111111156
JournalMedicina Oral, Patologia Oral y Cirugia Bucal
Volume13
Issue number6
Publication statusPublished - 01-06-2008

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All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology
  • Dentistry(all)

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