Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications

Goutam Thakur, Fiona Concy Rodrigues, Krizma Singh

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A popular approach to attaining controlled drug delivery from polymer based systems involves the use of cross-linkers. In order to improve the properties of polymers specific to their applications, they can be modified by either physical cross-linkers (high pressure, irradiation) or chemical cross-linkers (glutaraldehyde, genipin). This chapter provides an insight into the different types and mechanisms of cross-linking. It reviews the existing drug delivery systems to understand the effects of cross-linking in them. The recent applications of cross-linked polymeric drug delivery and tissue engineering systems are also discussed.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages213-231
Number of pages19
DOIs
Publication statusPublished - 01-01-2018

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1078
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Thakur, G., Rodrigues, F. C., & Singh, K. (2018). Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications. In Advances in Experimental Medicine and Biology (pp. 213-231). (Advances in Experimental Medicine and Biology; Vol. 1078). Springer New York LLC. https://doi.org/10.1007/978-981-13-0950-2_11