Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications

Goutam Thakur, Fiona Concy Rodrigues, Krizma Singh

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A popular approach to attaining controlled drug delivery from polymer based systems involves the use of cross-linkers. In order to improve the properties of polymers specific to their applications, they can be modified by either physical cross-linkers (high pressure, irradiation) or chemical cross-linkers (glutaraldehyde, genipin). This chapter provides an insight into the different types and mechanisms of cross-linking. It reviews the existing drug delivery systems to understand the effects of cross-linking in them. The recent applications of cross-linked polymeric drug delivery and tissue engineering systems are also discussed.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages213-231
Number of pages19
DOIs
Publication statusPublished - 01-01-2018

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1078
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

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Biopolymers
Tissue Engineering
Drug delivery
Tissue engineering
Crosslinking
Polymers
Controlled drug delivery
Glutaral
Drug Delivery Systems
Pharmaceutical Preparations
Irradiation
Pressure
genipin

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Thakur, G., Rodrigues, F. C., & Singh, K. (2018). Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications. In Advances in Experimental Medicine and Biology (pp. 213-231). (Advances in Experimental Medicine and Biology; Vol. 1078). Springer New York LLC. https://doi.org/10.1007/978-981-13-0950-2_11
Thakur, Goutam ; Rodrigues, Fiona Concy ; Singh, Krizma. / Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications. Advances in Experimental Medicine and Biology. Springer New York LLC, 2018. pp. 213-231 (Advances in Experimental Medicine and Biology).
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Thakur, G, Rodrigues, FC & Singh, K 2018, Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications. in Advances in Experimental Medicine and Biology. Advances in Experimental Medicine and Biology, vol. 1078, Springer New York LLC, pp. 213-231. https://doi.org/10.1007/978-981-13-0950-2_11

Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications. / Thakur, Goutam; Rodrigues, Fiona Concy; Singh, Krizma.

Advances in Experimental Medicine and Biology. Springer New York LLC, 2018. p. 213-231 (Advances in Experimental Medicine and Biology; Vol. 1078).

Research output: Chapter in Book/Report/Conference proceedingChapter

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Thakur G, Rodrigues FC, Singh K. Crosslinking Biopolymers for Advanced Drug Delivery and Tissue Engineering Applications. In Advances in Experimental Medicine and Biology. Springer New York LLC. 2018. p. 213-231. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-981-13-0950-2_11