Abstract
Objective: Extramedullary plasmacytoma (EMP) constitutes approximately 4% of all plasma cell neoplasms. It may present as the sole manifestation of plasma cell neoplasm, as a solitary plasmacytoma of the bone or as a consequence of multiple myeloma. This study was done to determine the role of fine needle aspiration cytology (FNAC) in the diagnosis of EMP. Study Design: In our study 8 cases of EMP at various sites were diagnosed on FNAC. In 3 patients EMP was the initial presentation of plasma cell neoplasm. In the remaining 5 patients the tumors occurred during the course of treatment for multiple myeloma. Results: The lesions were located at various anatomic sites, including lymph node, scalp, breast, jaw, rib, clavicle and soft tissue swelling in the retrosternal region. The smears prepared from the aspirates in all cases revealed numerous plasma cells at various stages of maturation, leading to a diagnosis of EMP. Radiologic and bone marrow findings also substantiated the diagnosis of multiple myeloma in all but 1 case. Conclusion: FNAC offers a rapid, reliable and accurate diagnosis of EMP and thus allows initiation of appropriate treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 255-258 |
| Number of pages | 4 |
| Journal | Acta Cytologica |
| Volume | 54 |
| Issue number | 3 |
| Publication status | Published - 2010 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Histology
Cite this
}
Cytodiagnosis of extramedullary plasmacytomas. / Goel, Garima; Rai, Sharada; Naik, Ramadas; Gupta, Astha; Baliga, Poornima; Sinha, Ruchi.
In: Acta Cytologica, Vol. 54, No. 3, 2010, p. 255-258.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cytodiagnosis of extramedullary plasmacytomas
AU - Goel, Garima
AU - Rai, Sharada
AU - Naik, Ramadas
AU - Gupta, Astha
AU - Baliga, Poornima
AU - Sinha, Ruchi
PY - 2010
Y1 - 2010
N2 - Objective: Extramedullary plasmacytoma (EMP) constitutes approximately 4% of all plasma cell neoplasms. It may present as the sole manifestation of plasma cell neoplasm, as a solitary plasmacytoma of the bone or as a consequence of multiple myeloma. This study was done to determine the role of fine needle aspiration cytology (FNAC) in the diagnosis of EMP. Study Design: In our study 8 cases of EMP at various sites were diagnosed on FNAC. In 3 patients EMP was the initial presentation of plasma cell neoplasm. In the remaining 5 patients the tumors occurred during the course of treatment for multiple myeloma. Results: The lesions were located at various anatomic sites, including lymph node, scalp, breast, jaw, rib, clavicle and soft tissue swelling in the retrosternal region. The smears prepared from the aspirates in all cases revealed numerous plasma cells at various stages of maturation, leading to a diagnosis of EMP. Radiologic and bone marrow findings also substantiated the diagnosis of multiple myeloma in all but 1 case. Conclusion: FNAC offers a rapid, reliable and accurate diagnosis of EMP and thus allows initiation of appropriate treatment.
AB - Objective: Extramedullary plasmacytoma (EMP) constitutes approximately 4% of all plasma cell neoplasms. It may present as the sole manifestation of plasma cell neoplasm, as a solitary plasmacytoma of the bone or as a consequence of multiple myeloma. This study was done to determine the role of fine needle aspiration cytology (FNAC) in the diagnosis of EMP. Study Design: In our study 8 cases of EMP at various sites were diagnosed on FNAC. In 3 patients EMP was the initial presentation of plasma cell neoplasm. In the remaining 5 patients the tumors occurred during the course of treatment for multiple myeloma. Results: The lesions were located at various anatomic sites, including lymph node, scalp, breast, jaw, rib, clavicle and soft tissue swelling in the retrosternal region. The smears prepared from the aspirates in all cases revealed numerous plasma cells at various stages of maturation, leading to a diagnosis of EMP. Radiologic and bone marrow findings also substantiated the diagnosis of multiple myeloma in all but 1 case. Conclusion: FNAC offers a rapid, reliable and accurate diagnosis of EMP and thus allows initiation of appropriate treatment.
UR - http://www.scopus.com/inward/record.url?scp=77953198118&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77953198118&partnerID=8YFLogxK
M3 - Article
VL - 54
SP - 255
EP - 258
JO - Acta Cytologica
JF - Acta Cytologica
SN - 0001-5547
IS - 3
ER -