Dehydrozingerone and its analogues as inhibitors of nonenzymatic lipid peroxidation

D.V. Rajakumar, M.N.A. Rao

Research output: Contribution to journalArticle

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Abstract

The antioxidant property of dehydrozingerone and its analogs were investigated in the ferric-ascorbate induced lipid peroxidation model in rat brain homogenate. All the non phenolic compounds were either inactive or less active, while phenolic compounds with substitution at both meta positions were found to be more active than dehydrozingerone. Based on their IC 50 values several of these compounds are more potent than vitamin E and hence may be of potential use in various diseases caused by oxidant stress.
Original languageUndefined/Unknown
Pages (from-to)516-519
Number of pages4
JournalPharmazie
Volume49
Issue number7
Publication statusPublished - 1994
Externally publishedYes

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