Several 3-chloro-1-[(2-phenylquinazolin-4-yl) oxy acetamidyl]-4- (substituted aryl)-2-azetidinones and 2-(substituted aryl)-3-[(2- phenylquinazolin-4-yl) oxy acetamidyl]-4-thiazolidinones were prepared by condensing 2-phenyl-4-(substituted benzylidine hydrazido methyloxy) quinazolines with chloroacetyl chloride and mercapto acetic acid respectively. These structures were established by IR and 1HNMR spectral data. These synthesized compounds were tested for their sedative, antibacterial and antifungal activities.
|Number of pages||6|
|Publication status||Published - 2008|
Panda, S. S., Chowdary, P. V. R., & Rani, S. (2008). Design and synthesis: Novel quinazolin incorporated azetidinones and thiazolidinones as sedative, antibacterial and antifungal agents. Indian Drugs, 45(2), 84-89.