A simple, precise and rapid RP-HPLC method was developed for the determination of ebastine in pharmaceutical formulations. The method was carried out on a Phenomenex RP-C18 column using a mixture of methanol and water (90:10) and detection was done at 262 nm. The linearity range was 5-100 μg/ml. The intra-day and inter-day precision were in the range of 0.22% to 0.49% and 0.24% to 0.73%, respectively.
Prabu, S., Kumar, C., & Shirwaikar, A. (2008). Determination of ebastine in pharmaceutical formulations by HPLC. Indian Journal of Pharmaceutical Sciences, 70(3), 406-407. https://doi.org/10.4103/0250-474X.43022