Development and evaluation of an optical -bre-based helium-neon laser irradiation system for tissue regeneration

A pilot study

Vijendra Prabhu, B. S Satish Rao, B. Nageshwara Rao, B. Kiran Aithal, B. Satish Shenoy, K. K. Mahato

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Low level laser therapy is being extensively used to treat various medical ailments including wound healing. In the present study, an optical fibre-based helium-neon (He-Ne) laser irradiation system was designed, developed and evaluated for optimum tissue repair on mice excision wounds. Circular wounds of 15 mm diameter were created on the dorsum of animals and single exposure of uniformly distributed laser beam was administered at 1, 2 and 3 J/cm2 to the respective test groups with suitable controls. Progression of healing was monitored by measuring wound contraction and mean healing time. Signiffcant reduction in wound size and mean healing time (p <0.001) were observed in the test groups for the laser dose of 2 J/cm2 compared to the unilluminated controls, suggesting the suitability of this dose.

Original languageEnglish
Pages (from-to)1287-1293
Number of pages7
JournalPramana - Journal of Physics
Volume75
Issue number6
Publication statusPublished - 12-2010

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helium-neon lasers
healing
regeneration
irradiation
evaluation
wound healing
dosage
progressions
contraction
lasers
mice
animals
therapy
optical fibers
laser beams

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

Cite this

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abstract = "Low level laser therapy is being extensively used to treat various medical ailments including wound healing. In the present study, an optical fibre-based helium-neon (He-Ne) laser irradiation system was designed, developed and evaluated for optimum tissue repair on mice excision wounds. Circular wounds of 15 mm diameter were created on the dorsum of animals and single exposure of uniformly distributed laser beam was administered at 1, 2 and 3 J/cm2 to the respective test groups with suitable controls. Progression of healing was monitored by measuring wound contraction and mean healing time. Signiffcant reduction in wound size and mean healing time (p <0.001) were observed in the test groups for the laser dose of 2 J/cm2 compared to the unilluminated controls, suggesting the suitability of this dose.",
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AU - Prabhu, Vijendra

AU - Rao, B. S Satish

AU - Rao, B. Nageshwara

AU - Aithal, B. Kiran

AU - Shenoy, B. Satish

AU - Mahato, K. K.

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AB - Low level laser therapy is being extensively used to treat various medical ailments including wound healing. In the present study, an optical fibre-based helium-neon (He-Ne) laser irradiation system was designed, developed and evaluated for optimum tissue repair on mice excision wounds. Circular wounds of 15 mm diameter were created on the dorsum of animals and single exposure of uniformly distributed laser beam was administered at 1, 2 and 3 J/cm2 to the respective test groups with suitable controls. Progression of healing was monitored by measuring wound contraction and mean healing time. Signiffcant reduction in wound size and mean healing time (p <0.001) were observed in the test groups for the laser dose of 2 J/cm2 compared to the unilluminated controls, suggesting the suitability of this dose.

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