Dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block in paediatrics for post-operative analgesia

Karl Sa Ribeiro, Anjali Ollapally, Julie Misquith

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Sensory blockade of the brachial plexus with local anaesthetics for perioperative analgesia leads to stable haemodynamics intraoperatively,smoother emergence from general anaesthesia and decreased need for supplemental analgesics or suppositories in the Post-operative period. However,increasing the duration of local anaesthetic action is often desirable because it prolongs surgical anaesthesia and analgesia. Various studies in adults prove that steroids increase the duration of action of local anaesthetics when used as adjuncts. Aim: The study aimed at determining the efficacy of dexamethasone as an adjuvant to bupivacaine for Post-operative analgesia following sensory blockade of the brachial plexus in paediatrics. Materials and Methods: The study was divided into two groups of 15 each,group BD receiving dexamethasone (0.1mg/ kg) as an adjunct to bupivacaine 0.125% and group B receiving bupivacaine alone. The duration of analgesia was taken as time from completion of the block to the patient receiving rescue analgesia,the haemodynamics were measured until 180 minutes after surgery,the incidence of Post-operative Nausea and Vomiting (PONV) was measured. Results: The duration of analgesia in the group BD was 27.1±13.4 hours and was significantly higher as compared to the group B,in which it was 13.9±11.3 hours (p<0.05). The pulse rate measured Post-operatively between both groups at 20 minutes (p-value 0.634),60 minutes (p-value 0.888),120 minutes (p-value 0.904) and 180 minutes (p-value 0.528) showed no statistical significance. Likewise the mean blood pressure measured between the two groups at 20 minutes,60 minutes,120 minutes and 180 minutes Post-operatively showed no significance. There was no significant difference in incidence of PONV in both groups with p-value of 0.624. Conclusion: Dexamethasone as an adjuvant to local anaesthetic in brachial plexus blocks significantly,prolongs duration of analgesia in children undergoing upper limb surgeries.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalJournal of Clinical and Diagnostic Research
Volume10
Issue number12
DOIs
Publication statusPublished - 01-12-2016

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Pediatrics
Bupivacaine
Local Anesthetics
Analgesia
Dexamethasone
Hemodynamics
Surgery
Suppositories
Nausea
Vomiting
Blood pressure
Anesthesia and Analgesia
Analgesics
Steroids
Incidence
Upper Extremity
General Anesthesia
Brachial Plexus Block
Heart Rate
Blood Pressure

All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

Cite this

@article{05d421da49cb472c82e99220c6d57e9e,
title = "Dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block in paediatrics for post-operative analgesia",
abstract = "Introduction: Sensory blockade of the brachial plexus with local anaesthetics for perioperative analgesia leads to stable haemodynamics intraoperatively,smoother emergence from general anaesthesia and decreased need for supplemental analgesics or suppositories in the Post-operative period. However,increasing the duration of local anaesthetic action is often desirable because it prolongs surgical anaesthesia and analgesia. Various studies in adults prove that steroids increase the duration of action of local anaesthetics when used as adjuncts. Aim: The study aimed at determining the efficacy of dexamethasone as an adjuvant to bupivacaine for Post-operative analgesia following sensory blockade of the brachial plexus in paediatrics. Materials and Methods: The study was divided into two groups of 15 each,group BD receiving dexamethasone (0.1mg/ kg) as an adjunct to bupivacaine 0.125{\%} and group B receiving bupivacaine alone. The duration of analgesia was taken as time from completion of the block to the patient receiving rescue analgesia,the haemodynamics were measured until 180 minutes after surgery,the incidence of Post-operative Nausea and Vomiting (PONV) was measured. Results: The duration of analgesia in the group BD was 27.1±13.4 hours and was significantly higher as compared to the group B,in which it was 13.9±11.3 hours (p<0.05). The pulse rate measured Post-operatively between both groups at 20 minutes (p-value 0.634),60 minutes (p-value 0.888),120 minutes (p-value 0.904) and 180 minutes (p-value 0.528) showed no statistical significance. Likewise the mean blood pressure measured between the two groups at 20 minutes,60 minutes,120 minutes and 180 minutes Post-operatively showed no significance. There was no significant difference in incidence of PONV in both groups with p-value of 0.624. Conclusion: Dexamethasone as an adjuvant to local anaesthetic in brachial plexus blocks significantly,prolongs duration of analgesia in children undergoing upper limb surgeries.",
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Dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block in paediatrics for post-operative analgesia. / Ribeiro, Karl Sa; Ollapally, Anjali; Misquith, Julie.

In: Journal of Clinical and Diagnostic Research, Vol. 10, No. 12, 01.12.2016, p. 1-4.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Dexamethasone as an adjuvant to bupivacaine in supraclavicular brachial plexus block in paediatrics for post-operative analgesia

AU - Ribeiro, Karl Sa

AU - Ollapally, Anjali

AU - Misquith, Julie

PY - 2016/12/1

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N2 - Introduction: Sensory blockade of the brachial plexus with local anaesthetics for perioperative analgesia leads to stable haemodynamics intraoperatively,smoother emergence from general anaesthesia and decreased need for supplemental analgesics or suppositories in the Post-operative period. However,increasing the duration of local anaesthetic action is often desirable because it prolongs surgical anaesthesia and analgesia. Various studies in adults prove that steroids increase the duration of action of local anaesthetics when used as adjuncts. Aim: The study aimed at determining the efficacy of dexamethasone as an adjuvant to bupivacaine for Post-operative analgesia following sensory blockade of the brachial plexus in paediatrics. Materials and Methods: The study was divided into two groups of 15 each,group BD receiving dexamethasone (0.1mg/ kg) as an adjunct to bupivacaine 0.125% and group B receiving bupivacaine alone. The duration of analgesia was taken as time from completion of the block to the patient receiving rescue analgesia,the haemodynamics were measured until 180 minutes after surgery,the incidence of Post-operative Nausea and Vomiting (PONV) was measured. Results: The duration of analgesia in the group BD was 27.1±13.4 hours and was significantly higher as compared to the group B,in which it was 13.9±11.3 hours (p<0.05). The pulse rate measured Post-operatively between both groups at 20 minutes (p-value 0.634),60 minutes (p-value 0.888),120 minutes (p-value 0.904) and 180 minutes (p-value 0.528) showed no statistical significance. Likewise the mean blood pressure measured between the two groups at 20 minutes,60 minutes,120 minutes and 180 minutes Post-operatively showed no significance. There was no significant difference in incidence of PONV in both groups with p-value of 0.624. Conclusion: Dexamethasone as an adjuvant to local anaesthetic in brachial plexus blocks significantly,prolongs duration of analgesia in children undergoing upper limb surgeries.

AB - Introduction: Sensory blockade of the brachial plexus with local anaesthetics for perioperative analgesia leads to stable haemodynamics intraoperatively,smoother emergence from general anaesthesia and decreased need for supplemental analgesics or suppositories in the Post-operative period. However,increasing the duration of local anaesthetic action is often desirable because it prolongs surgical anaesthesia and analgesia. Various studies in adults prove that steroids increase the duration of action of local anaesthetics when used as adjuncts. Aim: The study aimed at determining the efficacy of dexamethasone as an adjuvant to bupivacaine for Post-operative analgesia following sensory blockade of the brachial plexus in paediatrics. Materials and Methods: The study was divided into two groups of 15 each,group BD receiving dexamethasone (0.1mg/ kg) as an adjunct to bupivacaine 0.125% and group B receiving bupivacaine alone. The duration of analgesia was taken as time from completion of the block to the patient receiving rescue analgesia,the haemodynamics were measured until 180 minutes after surgery,the incidence of Post-operative Nausea and Vomiting (PONV) was measured. Results: The duration of analgesia in the group BD was 27.1±13.4 hours and was significantly higher as compared to the group B,in which it was 13.9±11.3 hours (p<0.05). The pulse rate measured Post-operatively between both groups at 20 minutes (p-value 0.634),60 minutes (p-value 0.888),120 minutes (p-value 0.904) and 180 minutes (p-value 0.528) showed no statistical significance. Likewise the mean blood pressure measured between the two groups at 20 minutes,60 minutes,120 minutes and 180 minutes Post-operatively showed no significance. There was no significant difference in incidence of PONV in both groups with p-value of 0.624. Conclusion: Dexamethasone as an adjuvant to local anaesthetic in brachial plexus blocks significantly,prolongs duration of analgesia in children undergoing upper limb surgeries.

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