Diabetes mellitus and HIV as co-morbidities in tuberculosis patients of rural South India

Soham Gupta, Vishnu Prasad Shenoy, Indira Bairy, Hiresave Srinivasa, Chiranjay Mukhopadhyay

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Objectives: Incidence of tuberculosis (TB) is greatest among patients with impaired immunity. India is experiencing a double epidemic of HIV and diabetes mellitus (DM), both of which are strongly associated with immuno-suppression. This study aimed to discover the prevalence of HIV and DM in both the pulmonary and extra-pulmonary TB patients of rural south India, retrospectively. Methods: Medical records of 192 microbiologically diagnosed pulmonary TB and 37 extra-pulmonary TB patients were thoroughly studied and data were extracted. The frequency distribution of HIV and DM was evaluated along with other demographic details such as age, sex and occupation in both groups. Results: The mean age of the pulmonary TB patients was 41.11. ±. 15.7 years, with significantly higher (p<. 0.0001) preponderance of DM (31.8%) over HIV (8.9%). 72.13% of the diabetic patients belonged to the age group of 41-60 years. Extra-pulmonary TB patients had a mean age of 34.62. ±. 12.9, years with a significantly higher (p<. 0.006) HIV prevalence of 32.43% over DM (5.4%). 75% of the HIV patients belonged to the age group of 41-60 years. Occupationally, the majority of the pulmonary TB patients were agricultural labourers (25.2%) while the majority of the extra-pulmonary TB patients were housewives or self employed (18.92%). Conclusion: Though more importance is being given to HIV-TB coinfection, we cannot overlook DM, which showed a significantly higher prevalence in pulmonary TB patients compared to HIV. The rising prevalence of DM in high TB burden countries may adversely affect TB control.

Original languageEnglish
Pages (from-to)140-144
Number of pages5
JournalJournal of Infection and Public Health
Volume4
Issue number3
DOIs
Publication statusPublished - 01-08-2011

Fingerprint

India
Diabetes Mellitus
Tuberculosis
Pulmonary Tuberculosis
HIV
Morbidity
Age Groups
Coinfection
Occupations
Medical Records
Immunity
Demography
Lung
Incidence

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

@article{f25703734d8b42788a21667ec0fceaa2,
title = "Diabetes mellitus and HIV as co-morbidities in tuberculosis patients of rural South India",
abstract = "Objectives: Incidence of tuberculosis (TB) is greatest among patients with impaired immunity. India is experiencing a double epidemic of HIV and diabetes mellitus (DM), both of which are strongly associated with immuno-suppression. This study aimed to discover the prevalence of HIV and DM in both the pulmonary and extra-pulmonary TB patients of rural south India, retrospectively. Methods: Medical records of 192 microbiologically diagnosed pulmonary TB and 37 extra-pulmonary TB patients were thoroughly studied and data were extracted. The frequency distribution of HIV and DM was evaluated along with other demographic details such as age, sex and occupation in both groups. Results: The mean age of the pulmonary TB patients was 41.11. ±. 15.7 years, with significantly higher (p<. 0.0001) preponderance of DM (31.8{\%}) over HIV (8.9{\%}). 72.13{\%} of the diabetic patients belonged to the age group of 41-60 years. Extra-pulmonary TB patients had a mean age of 34.62. ±. 12.9, years with a significantly higher (p<. 0.006) HIV prevalence of 32.43{\%} over DM (5.4{\%}). 75{\%} of the HIV patients belonged to the age group of 41-60 years. Occupationally, the majority of the pulmonary TB patients were agricultural labourers (25.2{\%}) while the majority of the extra-pulmonary TB patients were housewives or self employed (18.92{\%}). Conclusion: Though more importance is being given to HIV-TB coinfection, we cannot overlook DM, which showed a significantly higher prevalence in pulmonary TB patients compared to HIV. The rising prevalence of DM in high TB burden countries may adversely affect TB control.",
author = "Soham Gupta and Shenoy, {Vishnu Prasad} and Indira Bairy and Hiresave Srinivasa and Chiranjay Mukhopadhyay",
year = "2011",
month = "8",
day = "1",
doi = "10.1016/j.jiph.2011.03.005",
language = "English",
volume = "4",
pages = "140--144",
journal = "Journal of Infection and Public Health",
issn = "1876-0341",
publisher = "Elsevier BV",
number = "3",

}

Diabetes mellitus and HIV as co-morbidities in tuberculosis patients of rural South India. / Gupta, Soham; Shenoy, Vishnu Prasad; Bairy, Indira; Srinivasa, Hiresave; Mukhopadhyay, Chiranjay.

In: Journal of Infection and Public Health, Vol. 4, No. 3, 01.08.2011, p. 140-144.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Diabetes mellitus and HIV as co-morbidities in tuberculosis patients of rural South India

AU - Gupta, Soham

AU - Shenoy, Vishnu Prasad

AU - Bairy, Indira

AU - Srinivasa, Hiresave

AU - Mukhopadhyay, Chiranjay

PY - 2011/8/1

Y1 - 2011/8/1

N2 - Objectives: Incidence of tuberculosis (TB) is greatest among patients with impaired immunity. India is experiencing a double epidemic of HIV and diabetes mellitus (DM), both of which are strongly associated with immuno-suppression. This study aimed to discover the prevalence of HIV and DM in both the pulmonary and extra-pulmonary TB patients of rural south India, retrospectively. Methods: Medical records of 192 microbiologically diagnosed pulmonary TB and 37 extra-pulmonary TB patients were thoroughly studied and data were extracted. The frequency distribution of HIV and DM was evaluated along with other demographic details such as age, sex and occupation in both groups. Results: The mean age of the pulmonary TB patients was 41.11. ±. 15.7 years, with significantly higher (p<. 0.0001) preponderance of DM (31.8%) over HIV (8.9%). 72.13% of the diabetic patients belonged to the age group of 41-60 years. Extra-pulmonary TB patients had a mean age of 34.62. ±. 12.9, years with a significantly higher (p<. 0.006) HIV prevalence of 32.43% over DM (5.4%). 75% of the HIV patients belonged to the age group of 41-60 years. Occupationally, the majority of the pulmonary TB patients were agricultural labourers (25.2%) while the majority of the extra-pulmonary TB patients were housewives or self employed (18.92%). Conclusion: Though more importance is being given to HIV-TB coinfection, we cannot overlook DM, which showed a significantly higher prevalence in pulmonary TB patients compared to HIV. The rising prevalence of DM in high TB burden countries may adversely affect TB control.

AB - Objectives: Incidence of tuberculosis (TB) is greatest among patients with impaired immunity. India is experiencing a double epidemic of HIV and diabetes mellitus (DM), both of which are strongly associated with immuno-suppression. This study aimed to discover the prevalence of HIV and DM in both the pulmonary and extra-pulmonary TB patients of rural south India, retrospectively. Methods: Medical records of 192 microbiologically diagnosed pulmonary TB and 37 extra-pulmonary TB patients were thoroughly studied and data were extracted. The frequency distribution of HIV and DM was evaluated along with other demographic details such as age, sex and occupation in both groups. Results: The mean age of the pulmonary TB patients was 41.11. ±. 15.7 years, with significantly higher (p<. 0.0001) preponderance of DM (31.8%) over HIV (8.9%). 72.13% of the diabetic patients belonged to the age group of 41-60 years. Extra-pulmonary TB patients had a mean age of 34.62. ±. 12.9, years with a significantly higher (p<. 0.006) HIV prevalence of 32.43% over DM (5.4%). 75% of the HIV patients belonged to the age group of 41-60 years. Occupationally, the majority of the pulmonary TB patients were agricultural labourers (25.2%) while the majority of the extra-pulmonary TB patients were housewives or self employed (18.92%). Conclusion: Though more importance is being given to HIV-TB coinfection, we cannot overlook DM, which showed a significantly higher prevalence in pulmonary TB patients compared to HIV. The rising prevalence of DM in high TB burden countries may adversely affect TB control.

UR - http://www.scopus.com/inward/record.url?scp=80051682397&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80051682397&partnerID=8YFLogxK

U2 - 10.1016/j.jiph.2011.03.005

DO - 10.1016/j.jiph.2011.03.005

M3 - Article

VL - 4

SP - 140

EP - 144

JO - Journal of Infection and Public Health

JF - Journal of Infection and Public Health

SN - 1876-0341

IS - 3

ER -