Abstract
Metformin is recommended as the first-line therapy to treat type 2 diabetes mellitus with better efficacy. We present a young adult with severe fatigue and dyspnea along with difficulty during the walk and tingling sensation in both the lower limbs. He had T2DM for 9 years and continuing metformin 1 g daily for five years. He presented to the hospital with untreated wounds over lower limbs. His haematological reports showed the megaloblastic anemia and transfused with several pints of packed red blood cells (PRBCs). The patient developed sepsis during hospitalization and started on antibiotics. After several PRBC transfusions and aggressive treatment also patient did not improve and succumbed on 5th day of hospitalization.
| Original language | English |
|---|---|
| Pages (from-to) | 165-167 |
| Number of pages | 3 |
| Journal | Journal of Applied Pharmaceutical Science |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 01-03-2018 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmacology (medical)
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Diabetes mellitus and metformin : Fatal vitamin B12 deficiency associated with anemia and sepsis in a young adult. / Katroth, Anuvarsha; Narayanam, Anusha; Chauan, Sheetal; Singh, Ajit.
In: Journal of Applied Pharmaceutical Science, Vol. 8, No. 3, 01.03.2018, p. 165-167.Research output: Contribution to journal › Article
TY - JOUR
T1 - Diabetes mellitus and metformin
T2 - Fatal vitamin B12 deficiency associated with anemia and sepsis in a young adult
AU - Katroth, Anuvarsha
AU - Narayanam, Anusha
AU - Chauan, Sheetal
AU - Singh, Ajit
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Metformin is recommended as the first-line therapy to treat type 2 diabetes mellitus with better efficacy. We present a young adult with severe fatigue and dyspnea along with difficulty during the walk and tingling sensation in both the lower limbs. He had T2DM for 9 years and continuing metformin 1 g daily for five years. He presented to the hospital with untreated wounds over lower limbs. His haematological reports showed the megaloblastic anemia and transfused with several pints of packed red blood cells (PRBCs). The patient developed sepsis during hospitalization and started on antibiotics. After several PRBC transfusions and aggressive treatment also patient did not improve and succumbed on 5th day of hospitalization.
AB - Metformin is recommended as the first-line therapy to treat type 2 diabetes mellitus with better efficacy. We present a young adult with severe fatigue and dyspnea along with difficulty during the walk and tingling sensation in both the lower limbs. He had T2DM for 9 years and continuing metformin 1 g daily for five years. He presented to the hospital with untreated wounds over lower limbs. His haematological reports showed the megaloblastic anemia and transfused with several pints of packed red blood cells (PRBCs). The patient developed sepsis during hospitalization and started on antibiotics. After several PRBC transfusions and aggressive treatment also patient did not improve and succumbed on 5th day of hospitalization.
UR - http://www.scopus.com/inward/record.url?scp=85044746575&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044746575&partnerID=8YFLogxK
U2 - 10.7324/JAPS.2018.8322
DO - 10.7324/JAPS.2018.8322
M3 - Article
VL - 8
SP - 165
EP - 167
JO - Journal of Applied Pharmaceutical Science
JF - Journal of Applied Pharmaceutical Science
SN - 2231-3354
IS - 3
ER -