Dietary Spices in the Prevention of Rheumatoid Arthritis

Past, Present, and Future.

Manjeshwar Shrinath Baliga, Prajwal Prabhudev Mane, Jozy Timothy Nallemgera, Karadka Ramdas Thilakchand, Faizan Kalekhan

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Spices, defined by the US Food and Drug Administration as aromatic vegetable substances, in the whole, broken, or ground form, whose significant function in food is seasoning rather than nutrition, are an integral part of any Indian cuisine and are added to impart tastes, flavor, and color to the curries. In addition to their use in cooking, spices are also known to possess medicinal benefits and have been used in the various traditional and folk systems of medicine to treat ailments. Scientific studies carried out in the past have shown conclusively that most of the commonly used Indian spices and some of their phytochemicals possess antioxidant, free radical scavenging, anti-inflammatory, antibacterial, and antiviral effects; modulate detoxification enzymes, stimulate the immune system, reduce inflammation, and modulate steroid metabolism; and have antimutagenic, gastroprotective, and anticarcinogenic effects. Studies carried out during the past two decades have shown that commonly used Indian spices, such as fenugreek (. Trigonella foenum-graecum L., family Fabaceae), coriander (. Coriandrum sativum L., family Apiaceae), ginger (. Zingiber officinale Roscoe, family Zingiberaceae), turmeric (. Curcuma longa L., family Zingiberaceae), and their phytochemicals 6-shogaol (present in ginger), curcumin (present in turmeric), eugenol (present in clove Syzygium aromaticum L., family Myrtaceae), and thymoquinone (present in black cumin Nigella sativa L., family Ranunculaceae), possess beneficial effects in amelioration of rheumatoid arthritis in preclinical studies. Of these, ginger, turmeric and the oil of Nigella sativa have been shown also to possess beneficial effects in humans. For the first time, this chapter summarizes the findings from both preclinical and clinical studies with these spices and phytochemicals in rheumatoid arthritis, and also emphasizes the mechanisms of action responsible for the observed effects of each of the spices/phytochemicals.

Original languageEnglish
Title of host publicationFoods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults
PublisherElsevier Inc.
Pages41-49
Number of pages9
ISBN (Electronic)9780124186866
ISBN (Print)9780124186804
DOIs
Publication statusPublished - 27-01-2015
Externally publishedYes

Fingerprint

Spices
Ginger
Curcuma
Rheumatoid Arthritis
Phytochemicals
Coriandrum
Nigella sativa
Zingiberaceae
Trigonella
Syzygium
Myrtaceae
Antimutagenic Agents
Ranunculaceae
Anticarcinogenic Agents
Apiaceae
Eugenol
Curcumin
Cooking
Traditional Medicine
United States Food and Drug Administration

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Baliga, M. S., Mane, P. P., Timothy Nallemgera, J., Thilakchand, K. R., & Kalekhan, F. (2015). Dietary Spices in the Prevention of Rheumatoid Arthritis: Past, Present, and Future. In Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults (pp. 41-49). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-418680-4.00005-1
Baliga, Manjeshwar Shrinath ; Mane, Prajwal Prabhudev ; Timothy Nallemgera, Jozy ; Thilakchand, Karadka Ramdas ; Kalekhan, Faizan. / Dietary Spices in the Prevention of Rheumatoid Arthritis : Past, Present, and Future. Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults. Elsevier Inc., 2015. pp. 41-49
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Baliga, MS, Mane, PP, Timothy Nallemgera, J, Thilakchand, KR & Kalekhan, F 2015, Dietary Spices in the Prevention of Rheumatoid Arthritis: Past, Present, and Future. in Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults. Elsevier Inc., pp. 41-49. https://doi.org/10.1016/B978-0-12-418680-4.00005-1

Dietary Spices in the Prevention of Rheumatoid Arthritis : Past, Present, and Future. / Baliga, Manjeshwar Shrinath; Mane, Prajwal Prabhudev; Timothy Nallemgera, Jozy; Thilakchand, Karadka Ramdas; Kalekhan, Faizan.

Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults. Elsevier Inc., 2015. p. 41-49.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Baliga MS, Mane PP, Timothy Nallemgera J, Thilakchand KR, Kalekhan F. Dietary Spices in the Prevention of Rheumatoid Arthritis: Past, Present, and Future. In Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults. Elsevier Inc. 2015. p. 41-49 https://doi.org/10.1016/B978-0-12-418680-4.00005-1