Bir yetişkinde diffüz idiopatik kalsinosis kutis: Nadir bir vaka

Translated title of the contribution: Diffuse idiopathic calcinosis cutis in an adult: A rare case

Raghunath Prabhu, Yashdeep Sinha Sarma, Karan Phillip, Sakshi Sadhu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Idiopathic calcinosis cutis is a condition involving the deposition of calcium salts in the skin and subcutaneous tissue. The disease is a pathological condition of unknown origin and hence is idiopathic. The salt deposition is confined to areas such as the breast and vulva in females and scrotum and penis in males. Diffuse calcification with multiple complications in an adult is a rare entity. Only one such case has been reported in literature. A 59-year-old female presented to us with swelling of the right elbow, multiple calcific nodular lesions all over her fingers approximately 0.5x0.5 cm in size, and ulcers on her left great toe and right thumb with pain for the past two months. The ulcers were 2x2 cm and were observed to be healing without active discharge or signs of inflammation. The elbow was diffusely swollen and tender. Flexion deformity was present at the elbow. X-ray of hand and feet revealed calcinosis of the elbow and interphalangeal joints of the foot and hand. Blood tests revealed elevated C-reactive protein levels of 24 mg/dL, elevated Erythrocyte Sedimentation Rate (ESR) of 52 mm/ hr., serum calcium of 9.7 mg/dL and a serum phosphorous of 5 mg/ dL. Cultures from the foot ulcer were positive for methicillin-resistant staphylococcus aureus (MRSA). Workup for collagen vascular disease was negative. Histopathology confirmed calcinosis cutis. Treatment involved a conservative approach, including physiotherapy for the flexion deformity, antibiotics for MRSA, analgesics for pain relief and daily dressings. This case demonstrates that if a patient presents with multiple chalky nodular lesions with or without ulceration, pain and discharge involving areas of the upper limb or lower limb, diagnosis of idiopathic calcinosis cutis could be considered as a differential, despite its common confinement to the scrotum, breast, vulva and penis.

Original languageTurkish
Pages (from-to)131-134
Number of pages4
JournalEurasian Journal of Medicine
Volume46
Issue number2
DOIs
Publication statusPublished - 01-01-2014
Externally publishedYes

Fingerprint

Calcinosis
Elbow
Scrotum
Vulva
Penis
Methicillin-Resistant Staphylococcus aureus
Pain
Ulcer
Toe Joint
Breast
Salts
Hallux
Finger Joint
Foot Ulcer
Calcium
Elbow Joint
Collagen Diseases
Blood Sedimentation
Thumb
Subcutaneous Tissue

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Prabhu, Raghunath ; Sarma, Yashdeep Sinha ; Phillip, Karan ; Sadhu, Sakshi. / Bir yetişkinde diffüz idiopatik kalsinosis kutis : Nadir bir vaka. In: Eurasian Journal of Medicine. 2014 ; Vol. 46, No. 2. pp. 131-134.
@article{34a982bc424d4e72a2c666f625e0b341,
title = "Bir yetişkinde diff{\"u}z idiopatik kalsinosis kutis: Nadir bir vaka",
abstract = "Idiopathic calcinosis cutis is a condition involving the deposition of calcium salts in the skin and subcutaneous tissue. The disease is a pathological condition of unknown origin and hence is idiopathic. The salt deposition is confined to areas such as the breast and vulva in females and scrotum and penis in males. Diffuse calcification with multiple complications in an adult is a rare entity. Only one such case has been reported in literature. A 59-year-old female presented to us with swelling of the right elbow, multiple calcific nodular lesions all over her fingers approximately 0.5x0.5 cm in size, and ulcers on her left great toe and right thumb with pain for the past two months. The ulcers were 2x2 cm and were observed to be healing without active discharge or signs of inflammation. The elbow was diffusely swollen and tender. Flexion deformity was present at the elbow. X-ray of hand and feet revealed calcinosis of the elbow and interphalangeal joints of the foot and hand. Blood tests revealed elevated C-reactive protein levels of 24 mg/dL, elevated Erythrocyte Sedimentation Rate (ESR) of 52 mm/ hr., serum calcium of 9.7 mg/dL and a serum phosphorous of 5 mg/ dL. Cultures from the foot ulcer were positive for methicillin-resistant staphylococcus aureus (MRSA). Workup for collagen vascular disease was negative. Histopathology confirmed calcinosis cutis. Treatment involved a conservative approach, including physiotherapy for the flexion deformity, antibiotics for MRSA, analgesics for pain relief and daily dressings. This case demonstrates that if a patient presents with multiple chalky nodular lesions with or without ulceration, pain and discharge involving areas of the upper limb or lower limb, diagnosis of idiopathic calcinosis cutis could be considered as a differential, despite its common confinement to the scrotum, breast, vulva and penis.",
author = "Raghunath Prabhu and Sarma, {Yashdeep Sinha} and Karan Phillip and Sakshi Sadhu",
year = "2014",
month = "1",
day = "1",
doi = "10.5152/eajm.2014.29",
language = "Turkish",
volume = "46",
pages = "131--134",
journal = "Eurasian Journal of Medicine",
issn = "1308-8734",
publisher = "Aves",
number = "2",

}

Bir yetişkinde diffüz idiopatik kalsinosis kutis : Nadir bir vaka. / Prabhu, Raghunath; Sarma, Yashdeep Sinha; Phillip, Karan; Sadhu, Sakshi.

In: Eurasian Journal of Medicine, Vol. 46, No. 2, 01.01.2014, p. 131-134.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Bir yetişkinde diffüz idiopatik kalsinosis kutis

T2 - Nadir bir vaka

AU - Prabhu, Raghunath

AU - Sarma, Yashdeep Sinha

AU - Phillip, Karan

AU - Sadhu, Sakshi

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Idiopathic calcinosis cutis is a condition involving the deposition of calcium salts in the skin and subcutaneous tissue. The disease is a pathological condition of unknown origin and hence is idiopathic. The salt deposition is confined to areas such as the breast and vulva in females and scrotum and penis in males. Diffuse calcification with multiple complications in an adult is a rare entity. Only one such case has been reported in literature. A 59-year-old female presented to us with swelling of the right elbow, multiple calcific nodular lesions all over her fingers approximately 0.5x0.5 cm in size, and ulcers on her left great toe and right thumb with pain for the past two months. The ulcers were 2x2 cm and were observed to be healing without active discharge or signs of inflammation. The elbow was diffusely swollen and tender. Flexion deformity was present at the elbow. X-ray of hand and feet revealed calcinosis of the elbow and interphalangeal joints of the foot and hand. Blood tests revealed elevated C-reactive protein levels of 24 mg/dL, elevated Erythrocyte Sedimentation Rate (ESR) of 52 mm/ hr., serum calcium of 9.7 mg/dL and a serum phosphorous of 5 mg/ dL. Cultures from the foot ulcer were positive for methicillin-resistant staphylococcus aureus (MRSA). Workup for collagen vascular disease was negative. Histopathology confirmed calcinosis cutis. Treatment involved a conservative approach, including physiotherapy for the flexion deformity, antibiotics for MRSA, analgesics for pain relief and daily dressings. This case demonstrates that if a patient presents with multiple chalky nodular lesions with or without ulceration, pain and discharge involving areas of the upper limb or lower limb, diagnosis of idiopathic calcinosis cutis could be considered as a differential, despite its common confinement to the scrotum, breast, vulva and penis.

AB - Idiopathic calcinosis cutis is a condition involving the deposition of calcium salts in the skin and subcutaneous tissue. The disease is a pathological condition of unknown origin and hence is idiopathic. The salt deposition is confined to areas such as the breast and vulva in females and scrotum and penis in males. Diffuse calcification with multiple complications in an adult is a rare entity. Only one such case has been reported in literature. A 59-year-old female presented to us with swelling of the right elbow, multiple calcific nodular lesions all over her fingers approximately 0.5x0.5 cm in size, and ulcers on her left great toe and right thumb with pain for the past two months. The ulcers were 2x2 cm and were observed to be healing without active discharge or signs of inflammation. The elbow was diffusely swollen and tender. Flexion deformity was present at the elbow. X-ray of hand and feet revealed calcinosis of the elbow and interphalangeal joints of the foot and hand. Blood tests revealed elevated C-reactive protein levels of 24 mg/dL, elevated Erythrocyte Sedimentation Rate (ESR) of 52 mm/ hr., serum calcium of 9.7 mg/dL and a serum phosphorous of 5 mg/ dL. Cultures from the foot ulcer were positive for methicillin-resistant staphylococcus aureus (MRSA). Workup for collagen vascular disease was negative. Histopathology confirmed calcinosis cutis. Treatment involved a conservative approach, including physiotherapy for the flexion deformity, antibiotics for MRSA, analgesics for pain relief and daily dressings. This case demonstrates that if a patient presents with multiple chalky nodular lesions with or without ulceration, pain and discharge involving areas of the upper limb or lower limb, diagnosis of idiopathic calcinosis cutis could be considered as a differential, despite its common confinement to the scrotum, breast, vulva and penis.

UR - http://www.scopus.com/inward/record.url?scp=84902577925&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902577925&partnerID=8YFLogxK

U2 - 10.5152/eajm.2014.29

DO - 10.5152/eajm.2014.29

M3 - Article

AN - SCOPUS:84902577925

VL - 46

SP - 131

EP - 134

JO - Eurasian Journal of Medicine

JF - Eurasian Journal of Medicine

SN - 1308-8734

IS - 2

ER -