Abstract
Distal sensory polyneuropathy, which occur commonly in human immunodeficiency virus (HIV) patients can occur as a consequence of the disease itself or the antiretroviral treatment the patient is receiving. Among the antiretroviral agents, nucleoside analogues are commonly associated with neuropathy and the main underlying mechanism is thought to be the mitochondrial toxicity exhibited by these agents. Clinical presentation of antiretroviral induced neuropathy is similar to that associated with the HIV infection and in many patients they may overlap. Treatment is primarily symptomatic and certain pathogenesis-based approaches have shown promising results.
| Original language | English |
|---|---|
| Pages (from-to) | 81-87 |
| Number of pages | 7 |
| Journal | Annals of Indian Academy of Neurology |
| Volume | 10 |
| Issue number | 2 |
| Publication status | Published - 01-04-2007 |
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All Science Journal Classification (ASJC) codes
- Clinical Neurology
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Distal sensory polyneuropathy in human immunodeficiency virus patients and nucleoside analogue antiretroviral agents. / Jose, Jimmy; Saravu, Kavitha; Jimmy, Beena; Shastry, B.
In: Annals of Indian Academy of Neurology, Vol. 10, No. 2, 01.04.2007, p. 81-87.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Distal sensory polyneuropathy in human immunodeficiency virus patients and nucleoside analogue antiretroviral agents
AU - Jose, Jimmy
AU - Saravu, Kavitha
AU - Jimmy, Beena
AU - Shastry, B.
PY - 2007/4/1
Y1 - 2007/4/1
N2 - Distal sensory polyneuropathy, which occur commonly in human immunodeficiency virus (HIV) patients can occur as a consequence of the disease itself or the antiretroviral treatment the patient is receiving. Among the antiretroviral agents, nucleoside analogues are commonly associated with neuropathy and the main underlying mechanism is thought to be the mitochondrial toxicity exhibited by these agents. Clinical presentation of antiretroviral induced neuropathy is similar to that associated with the HIV infection and in many patients they may overlap. Treatment is primarily symptomatic and certain pathogenesis-based approaches have shown promising results.
AB - Distal sensory polyneuropathy, which occur commonly in human immunodeficiency virus (HIV) patients can occur as a consequence of the disease itself or the antiretroviral treatment the patient is receiving. Among the antiretroviral agents, nucleoside analogues are commonly associated with neuropathy and the main underlying mechanism is thought to be the mitochondrial toxicity exhibited by these agents. Clinical presentation of antiretroviral induced neuropathy is similar to that associated with the HIV infection and in many patients they may overlap. Treatment is primarily symptomatic and certain pathogenesis-based approaches have shown promising results.
UR - http://www.scopus.com/inward/record.url?scp=34447136003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34447136003&partnerID=8YFLogxK
M3 - Review article
VL - 10
SP - 81
EP - 87
JO - Annals of Indian Academy of Neurology
JF - Annals of Indian Academy of Neurology
SN - 0972-2327
IS - 2
ER -