TY - JOUR
T1 - Do mangrove habitats serve as a reservoir for Medicopsis romeroi, a clinically important fungus
AU - Devadatha, B.
AU - Prakash, Peralam Yegneswaran
AU - Jones, E. B.Gareth
AU - Sarma, V. V.
N1 - Funding Information:
We acknowledge with thanks the financial support received from the Ministry of Earth Sciences (MOES) through a funded project no. (Sanction order: MOES/36/OO1S/Extra/40/2014/PC-IV dt.14.1.2015). We also thank the Tamil Nadu Forest Department and DFO, Tiruvarur and Muthupet range officers. We thank the Department of Biotechnology, Pondicherry University, for providing us with laboratory facilities. The infrastructural support from SAP program of UGC and FIST program of DST for partial analyses of the work are gratefully acknowledged. B. Devadatha would like to thank the Ministry of Earth Sciences, Govt. of India, for providing a fellowship and Mr. Vijay Veeran and Mr. Venkatesan for their help during collection and lab works. E. B. Gareth Jones is supported under the Distinguished Scientist Fellowship Program (DSFP), King Saud University, Kingdom of Saudi Arabia. Peralam Yegneswaran Prakash thanks Ms. Asha for the assistance in mycology lab.
Publisher Copyright:
© 2020, German Mycological Society and Springer-Verlag GmbH Germany, part of Springer Nature.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/11
Y1 - 2020/11
N2 - Medicopsis romeroi is one of the frequent pathogens causing subcutaneous infections in immunocompromised patients. In this study, a sexual morph of Medicopsis romeroi was found on a decaying woody stem of the mangrove plant Suaeda monoica and its asexual morph was produced on malt extract agar. The sexual morph connection was established based on both morphological data and multigene phylogenetic analyses. Neomedicopsis chiangmaiensis comb. nov. is proposed by transferring Medicopsis chiangmaiensis to the genus Neomedicopsis based on morphology and multigene phylogenetic analyses. The preliminary pathogenicity tests on Medicopsis romeroi strain demonstrated beta haemolysin and esterase activities, and its ability to grow at 37 °C. It also exhibited strong activity in in vitro tests for aspartyl proteases, extracellular phospholipase, lipase and chitinase and mild activity for amylase and urease suggesting that this strain of Medicopsis romeroi, isolated from a mangrove habitat, could be an opportunistic pathogen to immunocompromised patients.
AB - Medicopsis romeroi is one of the frequent pathogens causing subcutaneous infections in immunocompromised patients. In this study, a sexual morph of Medicopsis romeroi was found on a decaying woody stem of the mangrove plant Suaeda monoica and its asexual morph was produced on malt extract agar. The sexual morph connection was established based on both morphological data and multigene phylogenetic analyses. Neomedicopsis chiangmaiensis comb. nov. is proposed by transferring Medicopsis chiangmaiensis to the genus Neomedicopsis based on morphology and multigene phylogenetic analyses. The preliminary pathogenicity tests on Medicopsis romeroi strain demonstrated beta haemolysin and esterase activities, and its ability to grow at 37 °C. It also exhibited strong activity in in vitro tests for aspartyl proteases, extracellular phospholipase, lipase and chitinase and mild activity for amylase and urease suggesting that this strain of Medicopsis romeroi, isolated from a mangrove habitat, could be an opportunistic pathogen to immunocompromised patients.
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U2 - 10.1007/s11557-020-01623-2
DO - 10.1007/s11557-020-01623-2
M3 - Article
AN - SCOPUS:85095681061
SN - 1617-416X
VL - 19
SP - 1267
EP - 1280
JO - Mycological Progress
JF - Mycological Progress
IS - 11
ER -