Does the glycated hemoglobin have an impact on atherogenic cholesterol in type 2 diabetes patients?

R. N. Devaki, B. K. Manjunatha Goud, Oinam Sarsina Devi, K. Deepa, Bhavna Nayal, Asha Prabhu, Naureen Anwar

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defective insulin secretion, insulin action or both. Studies on chronic complications of diabetes established the role of glycosylated hemoglobin (HbA1c) as a marker of evaluation of long term glycemic control and risk for chronic complications. This is a cross sectional study carried out on 40 diabetic patients and 50 normal individuals, between the age group of 40-60 years attending medicine OPD were included as study subjects. Diabetes was diagonsed based on laboratory and clinincal co-relation. 5ml of fasting venous sample was taken from study sujects and following parameters were estimated LDL, FPG and glycatedhemoglobin. The values of HbA1c and FPG were statistically significant in diabetic subjects when compared to controls (p< 0.001). The levels of LDL-C were increased in diabetic subjects but were not statistically significant. In conclusion, significant co-relation between HbA1c and LDL-C levels can be used as a potential biomarker for predicting dyslipidemia in type 2 diabetic patients in addition to long term glycemic control.

Original languageEnglish
Pages (from-to)303-307
Number of pages5
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Volume3
Issue number1
Publication statusPublished - 01-01-2012

Fingerprint

Glycosylated Hemoglobin A
Medical problems
Type 2 Diabetes Mellitus
Cholesterol
Insulin
Metabolic Diseases
Biomarkers
Diabetes Complications
Dyslipidemias
Hyperglycemia
Medicine
Fasting
Diabetes Mellitus
Age Groups
Cross-Sectional Studies
oxidized low density lipoprotein

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Devaki, R. N. ; Manjunatha Goud, B. K. ; Devi, Oinam Sarsina ; Deepa, K. ; Nayal, Bhavna ; Prabhu, Asha ; Anwar, Naureen. / Does the glycated hemoglobin have an impact on atherogenic cholesterol in type 2 diabetes patients?. In: Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2012 ; Vol. 3, No. 1. pp. 303-307.
@article{d81925ff7db945fc9642f1ebc1454bc5,
title = "Does the glycated hemoglobin have an impact on atherogenic cholesterol in type 2 diabetes patients?",
abstract = "Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defective insulin secretion, insulin action or both. Studies on chronic complications of diabetes established the role of glycosylated hemoglobin (HbA1c) as a marker of evaluation of long term glycemic control and risk for chronic complications. This is a cross sectional study carried out on 40 diabetic patients and 50 normal individuals, between the age group of 40-60 years attending medicine OPD were included as study subjects. Diabetes was diagonsed based on laboratory and clinincal co-relation. 5ml of fasting venous sample was taken from study sujects and following parameters were estimated LDL, FPG and glycatedhemoglobin. The values of HbA1c and FPG were statistically significant in diabetic subjects when compared to controls (p< 0.001). The levels of LDL-C were increased in diabetic subjects but were not statistically significant. In conclusion, significant co-relation between HbA1c and LDL-C levels can be used as a potential biomarker for predicting dyslipidemia in type 2 diabetic patients in addition to long term glycemic control.",
author = "Devaki, {R. N.} and {Manjunatha Goud}, {B. K.} and Devi, {Oinam Sarsina} and K. Deepa and Bhavna Nayal and Asha Prabhu and Naureen Anwar",
year = "2012",
month = "1",
day = "1",
language = "English",
volume = "3",
pages = "303--307",
journal = "Research Journal of Pharmaceutical, Biological and Chemical Sciences",
issn = "0975-8585",
publisher = "RJPBCS",
number = "1",

}

Does the glycated hemoglobin have an impact on atherogenic cholesterol in type 2 diabetes patients? / Devaki, R. N.; Manjunatha Goud, B. K.; Devi, Oinam Sarsina; Deepa, K.; Nayal, Bhavna; Prabhu, Asha; Anwar, Naureen.

In: Research Journal of Pharmaceutical, Biological and Chemical Sciences, Vol. 3, No. 1, 01.01.2012, p. 303-307.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Does the glycated hemoglobin have an impact on atherogenic cholesterol in type 2 diabetes patients?

AU - Devaki, R. N.

AU - Manjunatha Goud, B. K.

AU - Devi, Oinam Sarsina

AU - Deepa, K.

AU - Nayal, Bhavna

AU - Prabhu, Asha

AU - Anwar, Naureen

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defective insulin secretion, insulin action or both. Studies on chronic complications of diabetes established the role of glycosylated hemoglobin (HbA1c) as a marker of evaluation of long term glycemic control and risk for chronic complications. This is a cross sectional study carried out on 40 diabetic patients and 50 normal individuals, between the age group of 40-60 years attending medicine OPD were included as study subjects. Diabetes was diagonsed based on laboratory and clinincal co-relation. 5ml of fasting venous sample was taken from study sujects and following parameters were estimated LDL, FPG and glycatedhemoglobin. The values of HbA1c and FPG were statistically significant in diabetic subjects when compared to controls (p< 0.001). The levels of LDL-C were increased in diabetic subjects but were not statistically significant. In conclusion, significant co-relation between HbA1c and LDL-C levels can be used as a potential biomarker for predicting dyslipidemia in type 2 diabetic patients in addition to long term glycemic control.

AB - Diabetes mellitus is a group of metabolic disease characterized by hyperglycemia resulting from defective insulin secretion, insulin action or both. Studies on chronic complications of diabetes established the role of glycosylated hemoglobin (HbA1c) as a marker of evaluation of long term glycemic control and risk for chronic complications. This is a cross sectional study carried out on 40 diabetic patients and 50 normal individuals, between the age group of 40-60 years attending medicine OPD were included as study subjects. Diabetes was diagonsed based on laboratory and clinincal co-relation. 5ml of fasting venous sample was taken from study sujects and following parameters were estimated LDL, FPG and glycatedhemoglobin. The values of HbA1c and FPG were statistically significant in diabetic subjects when compared to controls (p< 0.001). The levels of LDL-C were increased in diabetic subjects but were not statistically significant. In conclusion, significant co-relation between HbA1c and LDL-C levels can be used as a potential biomarker for predicting dyslipidemia in type 2 diabetic patients in addition to long term glycemic control.

UR - http://www.scopus.com/inward/record.url?scp=84861939982&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861939982&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84861939982

VL - 3

SP - 303

EP - 307

JO - Research Journal of Pharmaceutical, Biological and Chemical Sciences

JF - Research Journal of Pharmaceutical, Biological and Chemical Sciences

SN - 0975-8585

IS - 1

ER -