Does there exist a steroid responsive inflammatory variant of dystrophic epidermolysis bullosa? - A case report

Abhishek De, R. C. Gharami, P. K. Datta, Raghavendra Rao

Research output: Contribution to journalArticle

Abstract

A six-year-old girl presented with extensive blisters, erosions and scarring over trauma prone areas which started soon after birth. The lesions were refractory to conservative treatment with antibiotics and dressings. Peripheral blood count showed eosinphilia and raised ESR. Histopathology showed subepidermal bulla with prominent eosinophilic and lymphocytic infiltrate in dermis. Direct and indirect immunofluorescence tests were negative proving our clinical diagnosis of dystrophic epidermolysis bullosa. We gave a trial of oral corticosteroid and patient's condition improved dramatically. She once again started developing new lesions once we tapered the drug. We propose an existence of steroid responsive inflammatory variant of epidermolysis bullosa; an observation which is supported by many earlier published evidences.

Original languageEnglish
Pages (from-to)115-119
Number of pages5
JournalJournal of Pakistan Association of Dermatologists
Volume20
Issue number2
Publication statusPublished - 01-04-2010

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Epidermolysis Bullosa Dystrophica
Blister
Steroids
Epidermolysis Bullosa
Direct Fluorescent Antibody Technique
Bandages
Dermis
Indirect Fluorescent Antibody Technique
Cicatrix
Adrenal Cortex Hormones
Observation
Parturition
Anti-Bacterial Agents
Wounds and Injuries
Pharmaceutical Preparations
Conservative Treatment

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

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Does there exist a steroid responsive inflammatory variant of dystrophic epidermolysis bullosa? - A case report. / De, Abhishek; Gharami, R. C.; Datta, P. K.; Rao, Raghavendra.

In: Journal of Pakistan Association of Dermatologists, Vol. 20, No. 2, 01.04.2010, p. 115-119.

Research output: Contribution to journalArticle

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