Abstract

Oral cancer together with pharyngeal cancer is the sixth most common malignancy reported worldwide and one with high mortality ratio among all malignancies [1]. Worldwide 450,000 new cases are estimated in 2014[2]. About 90% are a type of cancer called squamous cell carcinoma (SCC). SCC of the tongue is the most common oral malignancy accounting for approximately 40% of all oral carcinomas. One of the important factors for successful therapy of any malignancy is early diagnosis. Although considerable progress has been made in understanding the cellular and molecular mechanisms of tumorigenesis, lack of reliable diagnostic methods for early detection leading to delay in therapy is an important factor responsible for the increase in the mortality rate in various types of cancers. Spectroscopy techniques are extremely sensitive for the analysis of biochemical changes in cellular systems. These techniques can provide a valuable information on alterations that occur during the development of cancer. This is especially important in oral cancer, where "tumor detection is complicated by a tendency towards field cancerization, leading to multi-centric lesions" and "current techniques detect malignant change too late" [3], and "biopsies are not representative of the whole premalignant lesion". [4]

Original languageEnglish
Title of host publicationClinical and Biomedical Spectroscopy and Imaging IV
PublisherSPIE
Volume9537
ISBN (Electronic)9781628417029
DOIs
Publication statusPublished - 01-01-2015
EventClinical and Biomedical Spectroscopy and Imaging IV - Munich, Germany
Duration: 22-06-201524-06-2015

Conference

ConferenceClinical and Biomedical Spectroscopy and Imaging IV
CountryGermany
CityMunich
Period22-06-1524-06-15

Fingerprint

tongue
Fluorescence Spectrometry
Fluorescence spectroscopy
Tongue
laser induced fluorescence
Early Diagnosis
Lasers
cancer
Biopsy
spectroscopy
Tumors
Neoplasms
Spectroscopy
Mouth Neoplasms
mortality
Squamous Cell Carcinoma
lesions
therapy
Pharyngeal Neoplasms
Mortality

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

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title = "Early diagnosis of tongue malignancy using laser induced fluorescence spectroscopy technique",
abstract = "Oral cancer together with pharyngeal cancer is the sixth most common malignancy reported worldwide and one with high mortality ratio among all malignancies [1]. Worldwide 450,000 new cases are estimated in 2014[2]. About 90{\%} are a type of cancer called squamous cell carcinoma (SCC). SCC of the tongue is the most common oral malignancy accounting for approximately 40{\%} of all oral carcinomas. One of the important factors for successful therapy of any malignancy is early diagnosis. Although considerable progress has been made in understanding the cellular and molecular mechanisms of tumorigenesis, lack of reliable diagnostic methods for early detection leading to delay in therapy is an important factor responsible for the increase in the mortality rate in various types of cancers. Spectroscopy techniques are extremely sensitive for the analysis of biochemical changes in cellular systems. These techniques can provide a valuable information on alterations that occur during the development of cancer. This is especially important in oral cancer, where {"}tumor detection is complicated by a tendency towards field cancerization, leading to multi-centric lesions{"} and {"}current techniques detect malignant change too late{"} [3], and {"}biopsies are not representative of the whole premalignant lesion{"}. [4]",
author = "Ajeetkumar Patil and Unnikrishnan, {V. K.} and Ravikiran Ongole and Pai, {Keerthilatha M.} and Kartha, {V. B.} and Santhosh Chidangil",
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Patil, A, Unnikrishnan, VK, Ongole, R, Pai, KM, Kartha, VB & Chidangil, S 2015, Early diagnosis of tongue malignancy using laser induced fluorescence spectroscopy technique. in Clinical and Biomedical Spectroscopy and Imaging IV. vol. 9537, 95370J, SPIE, Clinical and Biomedical Spectroscopy and Imaging IV, Munich, Germany, 22-06-15. https://doi.org/10.1117/12.2184964

Early diagnosis of tongue malignancy using laser induced fluorescence spectroscopy technique. / Patil, Ajeetkumar; Unnikrishnan, V. K.; Ongole, Ravikiran; Pai, Keerthilatha M.; Kartha, V. B.; Chidangil, Santhosh.

Clinical and Biomedical Spectroscopy and Imaging IV. Vol. 9537 SPIE, 2015. 95370J.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

T1 - Early diagnosis of tongue malignancy using laser induced fluorescence spectroscopy technique

AU - Patil, Ajeetkumar

AU - Unnikrishnan, V. K.

AU - Ongole, Ravikiran

AU - Pai, Keerthilatha M.

AU - Kartha, V. B.

AU - Chidangil, Santhosh

PY - 2015/1/1

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N2 - Oral cancer together with pharyngeal cancer is the sixth most common malignancy reported worldwide and one with high mortality ratio among all malignancies [1]. Worldwide 450,000 new cases are estimated in 2014[2]. About 90% are a type of cancer called squamous cell carcinoma (SCC). SCC of the tongue is the most common oral malignancy accounting for approximately 40% of all oral carcinomas. One of the important factors for successful therapy of any malignancy is early diagnosis. Although considerable progress has been made in understanding the cellular and molecular mechanisms of tumorigenesis, lack of reliable diagnostic methods for early detection leading to delay in therapy is an important factor responsible for the increase in the mortality rate in various types of cancers. Spectroscopy techniques are extremely sensitive for the analysis of biochemical changes in cellular systems. These techniques can provide a valuable information on alterations that occur during the development of cancer. This is especially important in oral cancer, where "tumor detection is complicated by a tendency towards field cancerization, leading to multi-centric lesions" and "current techniques detect malignant change too late" [3], and "biopsies are not representative of the whole premalignant lesion". [4]

AB - Oral cancer together with pharyngeal cancer is the sixth most common malignancy reported worldwide and one with high mortality ratio among all malignancies [1]. Worldwide 450,000 new cases are estimated in 2014[2]. About 90% are a type of cancer called squamous cell carcinoma (SCC). SCC of the tongue is the most common oral malignancy accounting for approximately 40% of all oral carcinomas. One of the important factors for successful therapy of any malignancy is early diagnosis. Although considerable progress has been made in understanding the cellular and molecular mechanisms of tumorigenesis, lack of reliable diagnostic methods for early detection leading to delay in therapy is an important factor responsible for the increase in the mortality rate in various types of cancers. Spectroscopy techniques are extremely sensitive for the analysis of biochemical changes in cellular systems. These techniques can provide a valuable information on alterations that occur during the development of cancer. This is especially important in oral cancer, where "tumor detection is complicated by a tendency towards field cancerization, leading to multi-centric lesions" and "current techniques detect malignant change too late" [3], and "biopsies are not representative of the whole premalignant lesion". [4]

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