Effect of angiotensin converting enzyme inhibitor (captopril) on gastric ulcer production in pylorus ligated rats

S. P. Rao, A. Sathiamoorthy, S. S. Sathiamoorthy

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Intraperitoneal injection of Angiotensin Converting Enzyme inhibitor, captopril, reduced significantly (P < 0.001), the production of gastric ulcers in pylorus-ligated albino rats, compared to the control groups, irrespective of the dose schedule - single or quadruple. In the light of evidence available in the literature, it is reasonable to hypothesise that the anti-ulcer effect of captopril may be mediated through prostaglandins.

Original languageEnglish
Pages (from-to)296-298
Number of pages3
JournalIndian Journal of Physiology and Pharmacology
Volume39
Issue number3
Publication statusPublished - 01-01-1995
Externally publishedYes

Fingerprint

Captopril
Pylorus
Stomach Ulcer
Angiotensin-Converting Enzyme Inhibitors
Intraperitoneal Injections
Ulcer
Prostaglandins
Appointments and Schedules
Control Groups

All Science Journal Classification (ASJC) codes

  • Physiology
  • Pharmacology

Cite this

@article{fdfa40fc42e34676b75abacd2156bfa3,
title = "Effect of angiotensin converting enzyme inhibitor (captopril) on gastric ulcer production in pylorus ligated rats",
abstract = "Intraperitoneal injection of Angiotensin Converting Enzyme inhibitor, captopril, reduced significantly (P < 0.001), the production of gastric ulcers in pylorus-ligated albino rats, compared to the control groups, irrespective of the dose schedule - single or quadruple. In the light of evidence available in the literature, it is reasonable to hypothesise that the anti-ulcer effect of captopril may be mediated through prostaglandins.",
author = "Rao, {S. P.} and A. Sathiamoorthy and Sathiamoorthy, {S. S.}",
year = "1995",
month = "1",
day = "1",
language = "English",
volume = "39",
pages = "296--298",
journal = "Indian Journal of Physiology and Pharmacology",
issn = "0019-5499",
publisher = "Association of Physiologists and Pharmacologists of India",
number = "3",

}

Effect of angiotensin converting enzyme inhibitor (captopril) on gastric ulcer production in pylorus ligated rats. / Rao, S. P.; Sathiamoorthy, A.; Sathiamoorthy, S. S.

In: Indian Journal of Physiology and Pharmacology, Vol. 39, No. 3, 01.01.1995, p. 296-298.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effect of angiotensin converting enzyme inhibitor (captopril) on gastric ulcer production in pylorus ligated rats

AU - Rao, S. P.

AU - Sathiamoorthy, A.

AU - Sathiamoorthy, S. S.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Intraperitoneal injection of Angiotensin Converting Enzyme inhibitor, captopril, reduced significantly (P < 0.001), the production of gastric ulcers in pylorus-ligated albino rats, compared to the control groups, irrespective of the dose schedule - single or quadruple. In the light of evidence available in the literature, it is reasonable to hypothesise that the anti-ulcer effect of captopril may be mediated through prostaglandins.

AB - Intraperitoneal injection of Angiotensin Converting Enzyme inhibitor, captopril, reduced significantly (P < 0.001), the production of gastric ulcers in pylorus-ligated albino rats, compared to the control groups, irrespective of the dose schedule - single or quadruple. In the light of evidence available in the literature, it is reasonable to hypothesise that the anti-ulcer effect of captopril may be mediated through prostaglandins.

UR - http://www.scopus.com/inward/record.url?scp=0029113950&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029113950&partnerID=8YFLogxK

M3 - Article

VL - 39

SP - 296

EP - 298

JO - Indian Journal of Physiology and Pharmacology

JF - Indian Journal of Physiology and Pharmacology

SN - 0019-5499

IS - 3

ER -