Intraperitoneal injection of Angiotensin Converting Enzyme inhibitor, captopril, reduced significantly (P < 0.001), the production of gastric ulcers in pylorus-ligated albino rats, compared to the control groups, irrespective of the dose schedule - single or quadruple. In the light of evidence available in the literature, it is reasonable to hypothesise that the anti-ulcer effect of captopril may be mediated through prostaglandins.
|Number of pages||3|
|Journal||Indian Journal of Physiology and Pharmacology|
|Publication status||Published - 01-01-1995|
All Science Journal Classification (ASJC) codes