Effect of betamethasone valerate with biopolymer on skin inflammatory models in albino mice and wistar rats

M. C. Satish Kumar; Sachidananda Adiga; Avin D'Souza; Purnima Sirigiri; Deepa Ayappa; Veena Nayak; Bharti Chogtu; K. L. Bairy

Effect of betamethasone valerate with biopolymer on skin inflammatory models in albino mice and wistar rats

M. C. Satish Kumar, Sachidananda Adiga, Avin D'Souza, Purnima Sirigiri, Deepa Ayappa, Veena Nayak, Bharti Chogtu, K. L. Bairy

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1 Citation (Scopus)

Abstract

There is always a need for better antiflammatory drugs for conditions like atopic dermatitis. A newer formulation is biopolymer based betamethasone valerate. This study was done to compare the efficacy of betamethasone valerate with neomycin (Betnovate N) with betamethasone valerate with biopolymer in animal models of superficial skin inflammation in rats and mice. The inflammatory models croton oil ear edema in rats and topical application of arachadonic acid in mice were used. In both the models, the animals treated with betamethasone valerate with biopolymer showed a significant decrease in inflammation as compared to Betnovate N group.

Original language	English
Pages (from-to)	173-175
Number of pages	3
Journal	International Journal of Pharmaceutical Sciences Review and Research
Volume	4
Issue number	2
Publication status	Published - 01-09-2010

All Science Journal Classification (ASJC) codes

Pharmaceutical Science

Cite this

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abstract = "There is always a need for better antiflammatory drugs for conditions like atopic dermatitis. A newer formulation is biopolymer based betamethasone valerate. This study was done to compare the efficacy of betamethasone valerate with neomycin (Betnovate N) with betamethasone valerate with biopolymer in animal models of superficial skin inflammation in rats and mice. The inflammatory models croton oil ear edema in rats and topical application of arachadonic acid in mice were used. In both the models, the animals treated with betamethasone valerate with biopolymer showed a significant decrease in inflammation as compared to Betnovate N group.",

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AU - Adiga, Sachidananda

AU - D'Souza, Avin

AU - Sirigiri, Purnima

AU - Ayappa, Deepa

AU - Nayak, Veena

AU - Chogtu, Bharti

AU - Bairy, K. L.

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AB - There is always a need for better antiflammatory drugs for conditions like atopic dermatitis. A newer formulation is biopolymer based betamethasone valerate. This study was done to compare the efficacy of betamethasone valerate with neomycin (Betnovate N) with betamethasone valerate with biopolymer in animal models of superficial skin inflammation in rats and mice. The inflammatory models croton oil ear edema in rats and topical application of arachadonic acid in mice were used. In both the models, the animals treated with betamethasone valerate with biopolymer showed a significant decrease in inflammation as compared to Betnovate N group.

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Effect of betamethasone valerate with biopolymer on skin inflammatory models in albino mice and wistar rats

Abstract

All Science Journal Classification (ASJC) codes

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