Effect of cholesterol content on entrapment efficiency and influence of surfactant HLB on the vesicle size has been studied on sorbitan esters vesicles also known as niosomes prepared using a mechanical shaking technique without sonication. Primaquine phosphate was used as a model drug. Entrapment efficiency increased with increasing cholesterol content. Mean size of unsonicated niosomes showed a regular increase with increasing HLB from Span 85 (HLB 1.8) to Span 20 (HLB 8.6).
|Number of pages||3|
|Journal||Indian Journal of Pharmaceutical Sciences|
|Publication status||Published - 2004|
All Science Journal Classification (ASJC) codes
- Pharmaceutical Science