Effect of cigarette smoking on serum lipid, lipoprotein and apolipoprotein levels in hypertensives receiving β-adrenoreceptor blocking drugs

Ananthakrishnan Ramani, Sudhakar S. Nayak, A. R. Aroor, G. N. Kundaje

Research output: Contribution to journalArticle

Abstract

Both cigarette smoking and propranolol administration significantly alter plasma lipid profile. We examined the relationship of cigarette smoking and propranolol administration with fasting serum total cholesterol, triglyceride, lipoprotein cholesterol subfractions (high density, low density, and very low density), Apo-A, Apo-B and ratios obtained from these variables in 42 hypertensive patients. Significantly lower values of HDL cholesterol, Apo-A and HDL-C/total cholesterol and Apo-A/Apo-B ratios were observed in smokers taking propranolol than non-smokers not taking propranolol. Smokers who were not on propranolol also had significantly lower values as compared to non-smokers. These findings suggest that smoking may be the more significant factor responsible for alteration in lipid profile.

Original languageEnglish
Pages (from-to)59-64
Number of pages6
JournalIndian Journal of Clinical Biochemistry
Volume6
Issue number1
DOIs
Publication statusPublished - 01-01-1991

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All Science Journal Classification (ASJC) codes

  • Clinical Biochemistry

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