Effect of community-based yoga intervention on oxidative stress and glycemic parameters in prediabetes

A randomized controlled trial

Shreelaxmi V. Hegde, Prabha Adhikari, Sowmya Shetty, Poornima Manjrekar, Vivian D'Souza

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objectives: To study the effectiveness of yoga intervention on oxidative stress, glycemic status, blood pressure and anthropometry in prediabetes. Design: Randomized-controlled trial. Participants: Twenty nine prediabetes subjects aged 30-75 years. Setting: Yoga was conducted at 4 different community diabetes clinics in Mangalore, India. Interventions: Participants were randomized to either 3-month yoga or wait-list control groups. Main outcome measures: Malondialdehyde, glutathione, vitamin C, vitamin E, superoxide dismutase, plasma glucose, glycated haemoglobin, BMI, waist circumference, waist-to-hip ratio and blood pressure. Results: Yoga intervention resulted in a significant decline in malondialdehyde (p<. 0.001), relative to the control group. In comparison with the control, there was a significant improvement in BMI, waist circumference, systolic blood pressure and fasting glucose levels at follow-up. No significant improvement in glycated haemoglobin, waist-to-hip ratio or any of the antioxidants was observed. Conclusions: Yoga intervention may be helpful in control of oxidative stress in prediabetes subjects. Yoga can also be beneficial in reduction in BMI, waist circumference, systolic blood pressure and fasting glucose. Effect of yoga on antioxidant parameters was not evident in this study. The findings of this study need to be confirmed in larger trials involving active control groups.

Original languageEnglish
Pages (from-to)571-576
Number of pages6
JournalComplementary Therapies in Medicine
Volume21
Issue number6
DOIs
Publication statusPublished - 01-12-2013

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Yoga
Prediabetic State
Oxidative Stress
Randomized Controlled Trials
Blood Pressure
Waist Circumference
Waist-Hip Ratio
Glycosylated Hemoglobin A
Malondialdehyde
Glucose
Control Groups
Fasting
Antioxidants
Anthropometry
Vitamin E
Ascorbic Acid
Superoxide Dismutase
Glutathione
India
Outcome Assessment (Health Care)

All Science Journal Classification (ASJC) codes

  • Complementary and Manual Therapy
  • Complementary and alternative medicine
  • Advanced and Specialised Nursing

Cite this

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abstract = "Objectives: To study the effectiveness of yoga intervention on oxidative stress, glycemic status, blood pressure and anthropometry in prediabetes. Design: Randomized-controlled trial. Participants: Twenty nine prediabetes subjects aged 30-75 years. Setting: Yoga was conducted at 4 different community diabetes clinics in Mangalore, India. Interventions: Participants were randomized to either 3-month yoga or wait-list control groups. Main outcome measures: Malondialdehyde, glutathione, vitamin C, vitamin E, superoxide dismutase, plasma glucose, glycated haemoglobin, BMI, waist circumference, waist-to-hip ratio and blood pressure. Results: Yoga intervention resulted in a significant decline in malondialdehyde (p<. 0.001), relative to the control group. In comparison with the control, there was a significant improvement in BMI, waist circumference, systolic blood pressure and fasting glucose levels at follow-up. No significant improvement in glycated haemoglobin, waist-to-hip ratio or any of the antioxidants was observed. Conclusions: Yoga intervention may be helpful in control of oxidative stress in prediabetes subjects. Yoga can also be beneficial in reduction in BMI, waist circumference, systolic blood pressure and fasting glucose. Effect of yoga on antioxidant parameters was not evident in this study. The findings of this study need to be confirmed in larger trials involving active control groups.",
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Effect of community-based yoga intervention on oxidative stress and glycemic parameters in prediabetes : A randomized controlled trial. / Hegde, Shreelaxmi V.; Adhikari, Prabha; Shetty, Sowmya; Manjrekar, Poornima; D'Souza, Vivian.

In: Complementary Therapies in Medicine, Vol. 21, No. 6, 01.12.2013, p. 571-576.

Research output: Contribution to journalArticle

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AU - Manjrekar, Poornima

AU - D'Souza, Vivian

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