Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block

A prospective, randomised, double-blind study

Prashant A. Biradar, Padmanabha Kaimar, Kannappady Gopalakrishna

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Background: Different additives have been used to prolong brachial plexus block. We performed a prospective, randomised, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of supraclavicular brachial plexus block as this is the most common type of brachial block performed in our institute. Methods: Sixty American Society of Anaesthesiologist's physical status I and II patients undergoing elective hand, forearm and elbow surgery under brachial plexus block were randomly allocated to receive either 1.5% lidocaine (7 mg/ kg) with adrenaline (1:200, 000) and 2 ml of normal saline (group C, n=30) or 1.5% lidocaine (7 mg/ kg) with adrenaline (1:200, 000) and 2 ml of dexamethasone (8 mg) (group D, n=30). The block was performed using a nerve stimulator. Onset and duration of sensory and motor blockade were assessed. The sensory and motor blockade of radial, median, ulnar and musculocutaneous nerves were evaluated and recorded at 5, 10, 20, 120 min, and at every 30 min thereafter. Results: Two patients were excluded from the study because of block failure. The onset of sensory and motor blockade (13.4±2.8 vs. 16.0±2.3 min and 16.0±2.7 vs. 18.7±2.8 min, respectively) were significantly more rapid in the dexamethasone group than in the control group (P=0.001). The duration of sensory and motor blockade (326±58.6 vs. 159±20.1 and 290.6±52.7 vs. 135.5±20.3 min, respectively) were significantly longer in the dexamethasone group than in the control group (P=0.001). Conclusion: Addition of dexamethasone to 1.5% lidocaine with adrenaline in supraclavicular brachial plexus block speeds the onset and prolongs the duration of sensory and motor blockade.

Original languageEnglish
Pages (from-to)180-184
Number of pages5
JournalIndian Journal of Anaesthesia
Volume57
Issue number2
DOIs
Publication statusPublished - 01-03-2013
Externally publishedYes

Fingerprint

Lidocaine
Double-Blind Method
Dexamethasone
Epinephrine
Musculocutaneous Nerve
Radial Nerve
Control Groups
Ulnar Nerve
Median Nerve
Elbow
Forearm
Arm
Hand
Brachial Plexus Block

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

Biradar, Prashant A. ; Kaimar, Padmanabha ; Gopalakrishna, Kannappady. / Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block : A prospective, randomised, double-blind study. In: Indian Journal of Anaesthesia. 2013 ; Vol. 57, No. 2. pp. 180-184.
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abstract = "Background: Different additives have been used to prolong brachial plexus block. We performed a prospective, randomised, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of supraclavicular brachial plexus block as this is the most common type of brachial block performed in our institute. Methods: Sixty American Society of Anaesthesiologist's physical status I and II patients undergoing elective hand, forearm and elbow surgery under brachial plexus block were randomly allocated to receive either 1.5{\%} lidocaine (7 mg/ kg) with adrenaline (1:200, 000) and 2 ml of normal saline (group C, n=30) or 1.5{\%} lidocaine (7 mg/ kg) with adrenaline (1:200, 000) and 2 ml of dexamethasone (8 mg) (group D, n=30). The block was performed using a nerve stimulator. Onset and duration of sensory and motor blockade were assessed. The sensory and motor blockade of radial, median, ulnar and musculocutaneous nerves were evaluated and recorded at 5, 10, 20, 120 min, and at every 30 min thereafter. Results: Two patients were excluded from the study because of block failure. The onset of sensory and motor blockade (13.4±2.8 vs. 16.0±2.3 min and 16.0±2.7 vs. 18.7±2.8 min, respectively) were significantly more rapid in the dexamethasone group than in the control group (P=0.001). The duration of sensory and motor blockade (326±58.6 vs. 159±20.1 and 290.6±52.7 vs. 135.5±20.3 min, respectively) were significantly longer in the dexamethasone group than in the control group (P=0.001). Conclusion: Addition of dexamethasone to 1.5{\%} lidocaine with adrenaline in supraclavicular brachial plexus block speeds the onset and prolongs the duration of sensory and motor blockade.",
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Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block : A prospective, randomised, double-blind study. / Biradar, Prashant A.; Kaimar, Padmanabha; Gopalakrishna, Kannappady.

In: Indian Journal of Anaesthesia, Vol. 57, No. 2, 01.03.2013, p. 180-184.

Research output: Contribution to journalArticle

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