Effect of dietary fish on antioxidant parameters of normal and cholesterol stressed rats

M. Nandini, M. Abdul Rahiman, S. Narasimha Rao

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5 Citations (Scopus)


Feeding fish (Sardinella longiceps) to normal rats increased lipid peroxidation and total and Se-dependent glutathione peroxidase (GSH-px) activity in erythrocytes and manganese dependent superoxide dismutase (Mn-SOD) activity in liver. Feeding fish to cholesterol stressed rats showed a significant increase in the activity of GSH-px and cholesterol feeding alone, resulted in a significant increase in the lipid peroxidation and liver Mn-SOD activity. The results suggest that the high polyunsaturated fatty acid content of S. longiceps, the fish abundantly available in the west coast of India, does not have any deleterious effect by way of free radical generation. The observed lipid peroxidation is not critical as is evident from the results of glutathione level and other scavenging enzymes.

Original languageEnglish
Pages (from-to)1187-1191
Number of pages5
JournalIndian Journal of Experimental Biology
Issue number12
Publication statusPublished - 01-12-1999


All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Medicine(all)
  • Molecular Biology
  • Cell Biology

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