Effect of halobetasol propionate with biopolymer on skin inflammatory model in wistar rats

K. L. Bairy, Avinash M. Holla, Rockson Christopher, Purnima Sirigiri, A. V. Pawan Kumar, B. R. Chandrashekar, M. C. Satish Kumar

Research output: Contribution to journalArticle

Abstract

Various glucocorticoid preparations are used in atopic dermatitis to reduce inflammation. Halobetasol propionate is one such steroid used in atopic dermatitis. There is always a need for better antiflammatory drugs for conditions like atopic dermatitis. A newer formulation is biopolymer based halobetasol propionate .This study was done to compare the efficacy of halobetasol propionate with biopolymer with halobetasol propionate (Halovate) in croton oil ear edema model. In this model, the animals treated with halobetasol propionate with biopolymer showed a significant decrease in inflammation as compared to halobetasol propionate (Halovate).

Original languageEnglish
Pages (from-to)800-803
Number of pages4
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Volume4
Issue number3
Publication statusPublished - 01-07-2013
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Bairy, K. L., Holla, A. M., Christopher, R., Sirigiri, P., Pawan Kumar, A. V., Chandrashekar, B. R., & Satish Kumar, M. C. (2013). Effect of halobetasol propionate with biopolymer on skin inflammatory model in wistar rats. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 4(3), 800-803.