Effect of increased severity in patient specific stenosis of common carotid artery using CFD-a case study

S. M.Abdul Khader, B. Satish Shenoy, Raghuvir Pai, S. Ganesh Kamath, Nabeel Md Sharif, V. R.K. Rao

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The prevailing vascular fluid dynamics plays an important role in the development of atherosclerosis which is one of the most wide spread disease in humans. The recent advances in computational fluid dynamics (CFD) can be useful in observing the flow behavior downstream of the stenosis. The present study investigates a simple case of 66% eccentric stenosis of an approximate model generated from Doppler scan. The blood is assumed to be incompressible, homogenous and Newtonian, while artery is assumed to be a rigid wall. The transient analysis is performed using ANSYS-10.0, commercially available Finite Element Software. The flow pattern, Wall Shear Stress (WSS) and pressure contours are observed at pre-stenotic, throat and post-stenotic regions. In an attempt to predict the flow changes with varying the severity of stenosis, the percentage of stenosis is varied from 66% to 75%, 80%, 85%, 90%, 95% and analyzed. Comparison of results concludes that, with the increase in severity of stenosis, the flow changes abruptly causing an increase in velocity and WSS at throat region. The flow is highly turbulent in downstream leading to formation of eddies. The effect of back pressure is observed during late diastole which alters the flow behavior considerably in the downstream region.

Original languageEnglish
Pages (from-to)113-122
Number of pages10
JournalWorld Journal of Modelling and Simulation
Volume7
Issue number2
Publication statusPublished - 2011

Fingerprint

Stenosis
Arteries
Computational Fluid Dynamics
Shear stress
Computational fluid dynamics
Fluid dynamics
Wall Shear Stress
Transient analysis
Flow patterns
Blood
Atherosclerosis
Transient Analysis
Approximate Model
ANSYS
Flow Pattern
Fluid Dynamics
Doppler
Percentage
Finite Element
Predict

All Science Journal Classification (ASJC) codes

  • Modelling and Simulation
  • Engineering(all)

Cite this

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abstract = "The prevailing vascular fluid dynamics plays an important role in the development of atherosclerosis which is one of the most wide spread disease in humans. The recent advances in computational fluid dynamics (CFD) can be useful in observing the flow behavior downstream of the stenosis. The present study investigates a simple case of 66{\%} eccentric stenosis of an approximate model generated from Doppler scan. The blood is assumed to be incompressible, homogenous and Newtonian, while artery is assumed to be a rigid wall. The transient analysis is performed using ANSYS-10.0, commercially available Finite Element Software. The flow pattern, Wall Shear Stress (WSS) and pressure contours are observed at pre-stenotic, throat and post-stenotic regions. In an attempt to predict the flow changes with varying the severity of stenosis, the percentage of stenosis is varied from 66{\%} to 75{\%}, 80{\%}, 85{\%}, 90{\%}, 95{\%} and analyzed. Comparison of results concludes that, with the increase in severity of stenosis, the flow changes abruptly causing an increase in velocity and WSS at throat region. The flow is highly turbulent in downstream leading to formation of eddies. The effect of back pressure is observed during late diastole which alters the flow behavior considerably in the downstream region.",
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Effect of increased severity in patient specific stenosis of common carotid artery using CFD-a case study. / Khader, S. M.Abdul; Shenoy, B. Satish; Pai, Raghuvir; Kamath, S. Ganesh; Sharif, Nabeel Md; Rao, V. R.K.

In: World Journal of Modelling and Simulation, Vol. 7, No. 2, 2011, p. 113-122.

Research output: Contribution to journalArticle

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AU - Sharif, Nabeel Md

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