Effect of indomethacin and indomethacin copper on wound healing

K. L. Bairy, S. N. Somayaji

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1 Citation (Scopus)

Abstract

There are reports that some non steroidal antiinflammatory drugs (NSAIDs) have healing suppressant activity and this activity can be alleviated by incorporating copper into them. A study was undertaken to compare indomethacin and its copper complex on wound healing profiles in male albino rats. Incision and dead space wound models were used in this study. Indomethacin-copper (Ind-Cu) significantly reversed the suppressant effect of indomethacin on gain in breaking strength of incision and dead space wounds. Ind-Cu shared the suppressant effect of indomethacin on granuloma formation and its collagen content.

Original languageEnglish
Pages (from-to)706-709
Number of pages4
JournalIndian Drugs
Volume36
Issue number11
Publication statusPublished - 01-12-1999
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery

Cite this

Bairy, K. L., & Somayaji, S. N. (1999). Effect of indomethacin and indomethacin copper on wound healing. Indian Drugs, 36(11), 706-709.