Effect of indomethacin and indomethacin copper on wound healing

K. L. Bairy, S. N. Somayaji

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

There are reports that some non steroidal antiinflammatory drugs (NSAIDs) have healing suppressant activity and this activity can be alleviated by incorporating copper into them. A study was undertaken to compare indomethacin and its copper complex on wound healing profiles in male albino rats. Incision and dead space wound models were used in this study. Indomethacin-copper (Ind-Cu) significantly reversed the suppressant effect of indomethacin on gain in breaking strength of incision and dead space wounds. Ind-Cu shared the suppressant effect of indomethacin on granuloma formation and its collagen content.

Original languageEnglish
Pages (from-to)706-709
Number of pages4
JournalIndian Drugs
Volume36
Issue number11
Publication statusPublished - 01-12-1999
Externally publishedYes

Fingerprint

Indomethacin
Wound Healing
Copper
Space Simulation
Wounds and Injuries
Granuloma
Anti-Inflammatory Agents
Collagen
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery

Cite this

Bairy, K. L., & Somayaji, S. N. (1999). Effect of indomethacin and indomethacin copper on wound healing. Indian Drugs, 36(11), 706-709.
Bairy, K. L. ; Somayaji, S. N. / Effect of indomethacin and indomethacin copper on wound healing. In: Indian Drugs. 1999 ; Vol. 36, No. 11. pp. 706-709.
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Bairy, KL & Somayaji, SN 1999, 'Effect of indomethacin and indomethacin copper on wound healing', Indian Drugs, vol. 36, no. 11, pp. 706-709.

Effect of indomethacin and indomethacin copper on wound healing. / Bairy, K. L.; Somayaji, S. N.

In: Indian Drugs, Vol. 36, No. 11, 01.12.1999, p. 706-709.

Research output: Contribution to journalArticle

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Bairy KL, Somayaji SN. Effect of indomethacin and indomethacin copper on wound healing. Indian Drugs. 1999 Dec 1;36(11):706-709.