The alcoholic extract of the flowers of Ixora coccinea was studied for its effect on wound healing, using a dead space wound model in rats. Significant increases in granuloma tissue weight, tensile strength, hydroxyproline and glycosaminoglycan content were observed. The prohealing actions seem to be due to increased collagen deposition as well as better alignment and maturation. The drug induced a hypertropic effect on the thymus gland but had no effect on the adrenals.
All Science Journal Classification (ASJC) codes
- Drug Discovery