Effect of limited access dressing on hydroxyproline and enzymatic antioxidant status in nonhealing chronic ulcers

Thittamaranahalli Muguregowda Honnegowda, Pramod Kumar, Padmanabha Udupa, Pragna Rao, Siddhartha Bhandary, Krishna Kumar Mahato, Anurag Sharan, Shreemathi S. Mayya

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Healing ability of nonhealing chronic ulcers can be assessed by estimating hydroxyproline, total protein and enzymatic antioxidants such as glutathione peroxidase (GPx), glutathione S-transferase (GST) in the granulation tissue. Materials and Method: A total of 34 patients were analysed from two groups: Limited access dressing (LAD) group (n = 17) and conventional dressing group (n = 17). Results: Patients treated with LAD that exerts combination of intermittent negative pressure and moist wound-healing had shown a significant increase in the hydroxyproline (P = 0.026), total protein (P = 0.004), GPx level (P = 0.030) and GST level (P = 0.045). Conclusion: Patients treated with LAD indicated significantly better anabolic effect on wound-healing compared to that of patients treated with conventional dressing.

Original languageEnglish
Pages (from-to)216-220
Number of pages5
JournalIndian Journal of Plastic Surgery
Volume47
Issue number2
DOIs
Publication statusPublished - 2014

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Hydroxyproline
Bandages
Ulcer
Antioxidants
Glutathione Peroxidase
Glutathione Transferase
Wound Healing
Anabolic Agents
Granulation Tissue
Proteins
Pressure

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Honnegowda, Thittamaranahalli Muguregowda ; Kumar, Pramod ; Udupa, Padmanabha ; Rao, Pragna ; Bhandary, Siddhartha ; Mahato, Krishna Kumar ; Sharan, Anurag ; Mayya, Shreemathi S. / Effect of limited access dressing on hydroxyproline and enzymatic antioxidant status in nonhealing chronic ulcers. In: Indian Journal of Plastic Surgery. 2014 ; Vol. 47, No. 2. pp. 216-220.
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Effect of limited access dressing on hydroxyproline and enzymatic antioxidant status in nonhealing chronic ulcers. / Honnegowda, Thittamaranahalli Muguregowda; Kumar, Pramod; Udupa, Padmanabha; Rao, Pragna; Bhandary, Siddhartha; Mahato, Krishna Kumar; Sharan, Anurag; Mayya, Shreemathi S.

In: Indian Journal of Plastic Surgery, Vol. 47, No. 2, 2014, p. 216-220.

Research output: Contribution to journalArticle

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T1 - Effect of limited access dressing on hydroxyproline and enzymatic antioxidant status in nonhealing chronic ulcers

AU - Honnegowda, Thittamaranahalli Muguregowda

AU - Kumar, Pramod

AU - Udupa, Padmanabha

AU - Rao, Pragna

AU - Bhandary, Siddhartha

AU - Mahato, Krishna Kumar

AU - Sharan, Anurag

AU - Mayya, Shreemathi S.

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