Effect of lupeol isolated from Crataeva nurvala Buch.- Ham. stem bark extract against free radical induced nephrotoxicity in rats

A. Shirwaikar, M. Manjunath Setty, P. Bommu, B. Krishnanand

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Lupeol, isolated from Crataeva nurvala stem bark in doses 40 and 80 mg/kg body weight, po, for 10 days, decreased the concentration of blood urea nitrogen, creatinine and lipid peroxidation and increased glutathione and catalase activities in cisplatin (5 mg/kg body weight, ip) induced nephrotoxicity in rats. The increased glutathione and catalase activities are indicative of antioxidant properties of lupeol.
Original languageEnglish
Pages (from-to)686-690
Number of pages5
JournalIndian Journal of Experimental Biology
Volume42
Issue number7
Publication statusPublished - 2004

    Fingerprint

Cite this