Effect of maternal perceived stress during pregnancy on gestational diabetes mellitus risk: A prospective case-control study

Surabhi Mishra, Avinash Shetty, Chythra R. Rao, Sathisha Nayak, Asha Kamath

Research output: Contribution to journalArticle

Abstract

Background and aims: A variety of risk factors have been reported for the development of gestational diabetes mellitus (GDM). But limited review on the role of antenatal perceived stress necessitated the design of the present study to evaluate the association between GDM and perceived stress during pregnancy. Methods: A prospective case-control study was carried out among 100 GDM cases and 273 matched controls, attending regular antenatal clinic at two private hospitals of Karnataka. Data was collected by personal interviews using a standard questionnaire. Perceived stress was assessed using the Cohen 10-item Perceived Stress Scale. Score of ≥20 was identified as high stress. Statistical Package for the Social Sciences version 15 was used for analysis. Results: Exposure rates for high maternal perceived stress among cases during pregnancy were noted. The odds of GDM were 13 folds higher among those with high antenatal stress (≥20) compared to those with low (<20) (p < 0.001) perceived stress. No correlation between maternal antenatal stress and blood glucose following OGTT was noted. Conclusions: The study identified high perceived stress during pregnancy as a potential risk factor for GDM.

Original languageEnglish
Pages (from-to)1163-1169
Number of pages7
JournalDiabetes and Metabolic Syndrome: Clinical Research and Reviews
Volume14
Issue number5
DOIs
Publication statusPublished - 01-09-2020

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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