Effect of novel chalcone derivatives on clinical isolates of multidrug resistant bacterial strains

Mallika Maiya, S. J. Akshatha, K. L. Shobha, Vivekananda Shenoy, K. Subrahmanya Bhat

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We synthesized and studied the efficacy of hydroxy and corresponding tosyloxy chalcone derivatives to inhibit the growth of MDR strains of bacteria. The required compounds were synthesized using literature methods and characterized by spectroscopic techniques. Bacterial strains were isolated by clinical methods. Our studies show hydroxy chalcone derivative is effective in inhibiting the growth of MDR bacterial strains whereas tosyl derivative is inactive.

Original languageEnglish
Pages (from-to)466-470
Number of pages5
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Volume6
Issue number2
Publication statusPublished - 01-01-2015

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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